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Insights into non-autoimmune type 1 diabetes with 13 novel loci in low polygenic risk score patients

Insights into non-autoimmune type 1 diabetes with 13 novel loci in low polygenic risk score patients

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_ed9a2299120543618940a4496e3810ca

Insights into non-autoimmune type 1 diabetes with 13 novel loci in low polygenic risk score patients

About this item

Full title

Insights into non-autoimmune type 1 diabetes with 13 novel loci in low polygenic risk score patients

Publisher

London: Nature Publishing Group UK

Journal title

Scientific reports, 2021-08, Vol.11 (1), p.16013-16013, Article 16013

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

With polygenic risk score (PRS) for autoimmune type 1 diabetes (T1D), this study identified T1D cases with low T1D PRS and searched for susceptibility loci in these cases. Our hypothesis is that genetic effects (likely mediated by relatively rare genetic variants) of non-mainstream (or non-autoimmune) T1D might have been diluted in the previous stu...

Alternative Titles

Full title

Insights into non-autoimmune type 1 diabetes with 13 novel loci in low polygenic risk score patients

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_ed9a2299120543618940a4496e3810ca

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_ed9a2299120543618940a4496e3810ca

Other Identifiers

ISSN

2045-2322

E-ISSN

2045-2322

DOI

10.1038/s41598-021-94994-9

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