A moisture-tolerant route to unprotected α/β-amino acid N-carboxyanhydrides and facile synthesis of...
A moisture-tolerant route to unprotected α/β-amino acid N-carboxyanhydrides and facile synthesis of hyperbranched polypeptides
About this item
Full title
Author / Creator
Tian, Zi-You , Zhang, Zhengchu , Wang, Shuo and Lu, Hua
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
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Publication information
Publisher
London: Nature Publishing Group UK
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More information
Scope and Contents
Contents
A great hurdle in the production of synthetic polypeptides lies in the access of
N
-carboxyanhydrides (NCA) monomers, which requires dry solvents, Schlenk line/gloveboxe, and protection of side-chain functional groups. Here we report a robust method for preparing unprotected NCA monomers in air and under moisture. The method employs epoxy com...
Alternative Titles
Full title
A moisture-tolerant route to unprotected α/β-amino acid N-carboxyanhydrides and facile synthesis of hyperbranched polypeptides
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Author / Creator
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Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_eda2208a5aff400f8ef4cbb4af82d0a5
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_eda2208a5aff400f8ef4cbb4af82d0a5
Other Identifiers
ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-021-25689-y
