Heparin-induced tau filaments are polymorphic and differ from those in Alzheimer's and Pick's diseas...
Heparin-induced tau filaments are polymorphic and differ from those in Alzheimer's and Pick's diseases
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Publisher
England: eLife Sciences Publications Ltd
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Language
English
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England: eLife Sciences Publications Ltd
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Contents
Assembly of microtubule-associated protein tau into filamentous inclusions underlies a range of neurodegenerative diseases. Tau filaments adopt different conformations in Alzheimer's and Pick's diseases. Here, we used cryo- and immuno- electron microscopy to characterise filaments that were assembled from recombinant full-length human tau with four...
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Full title
Heparin-induced tau filaments are polymorphic and differ from those in Alzheimer's and Pick's diseases
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TN_cdi_doaj_primary_oai_doaj_org_article_ee4f6398c129456c86cb564b7b6c494a
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_ee4f6398c129456c86cb564b7b6c494a
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ISSN
2050-084X
E-ISSN
2050-084X
DOI
10.7554/eLife.43584
