Pain-causing stinging nettle toxins target TMEM233 to modulate NaV1.7 function
Pain-causing stinging nettle toxins target TMEM233 to modulate NaV1.7 function
About this item
Full title
Author / Creator
Jami, Sina , Deuis, Jennifer R. , Klasfauseweh, Tabea , Cheng, Xiaoyang , Kurdyukov, Sergey , Chung, Felicity , Okorokov, Andrei L. , Li, Shengnan , Zhang, Jiangtao , Cristofori-Armstrong, Ben , Israel, Mathilde R. , Ju, Robert J. , Robinson, Samuel D. , Zhao, Peng , Ragnarsson, Lotten , Andersson, Åsa , Tran, Poanna , Schendel, Vanessa , McMahon, Kirsten L. , Tran, Hue N. T. , Chin, Yanni K.-Y. , Zhu, Yifei , Liu, Junyu , Crawford, Theo , Purushothamvasan, Saipriyaa , Habib, Abdella M. , Andersson, David A. , Rash, Lachlan D. , Wood, John N. , Zhao, Jing , Stehbens, Samantha J. , Mobli, Mehdi , Leffler, Andreas , Jiang, Daohua , Cox, James J. , Waxman, Stephen G. , Dib-Hajj, Sulayman D. , Neely, G. Gregory , Durek, Thomas and Vetter, Irina
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
Formats
Publication information
Publisher
London: Nature Publishing Group UK
Subjects
More information
Scope and Contents
Contents
Voltage-gated sodium (Na
V
) channels are critical regulators of neuronal excitability and are targeted by many toxins that directly interact with the pore-forming α subunit, typically via extracellular loops of the voltage-sensing domains, or residues forming part of the pore domain. Excelsatoxin A (ExTxA), a pain-causing knottin peptide fro...
Alternative Titles
Full title
Pain-causing stinging nettle toxins target TMEM233 to modulate NaV1.7 function
Authors, Artists and Contributors
Author / Creator
Deuis, Jennifer R.
Klasfauseweh, Tabea
Cheng, Xiaoyang
Kurdyukov, Sergey
Chung, Felicity
Okorokov, Andrei L.
Li, Shengnan
Zhang, Jiangtao
Cristofori-Armstrong, Ben
Israel, Mathilde R.
Ju, Robert J.
Robinson, Samuel D.
Zhao, Peng
Ragnarsson, Lotten
Andersson, Åsa
Tran, Poanna
Schendel, Vanessa
McMahon, Kirsten L.
Tran, Hue N. T.
Chin, Yanni K.-Y.
Zhu, Yifei
Liu, Junyu
Crawford, Theo
Purushothamvasan, Saipriyaa
Habib, Abdella M.
Andersson, David A.
Rash, Lachlan D.
Wood, John N.
Zhao, Jing
Stehbens, Samantha J.
Mobli, Mehdi
Leffler, Andreas
Jiang, Daohua
Cox, James J.
Waxman, Stephen G.
Dib-Hajj, Sulayman D.
Neely, G. Gregory
Durek, Thomas
Vetter, Irina
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_ef7fee6301d340c5b67edc494cc4b801
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_ef7fee6301d340c5b67edc494cc4b801
Other Identifiers
ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-023-37963-2
