Quantitative Measurements of LRRK2 in Human Cerebrospinal Fluid Demonstrates Increased Levels in G20...
Quantitative Measurements of LRRK2 in Human Cerebrospinal Fluid Demonstrates Increased Levels in G2019S Patients
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Lausanne: Frontiers Research Foundation
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English
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Lausanne: Frontiers Research Foundation
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Leucine-rich repeat kinase 2 (LRRK2) mutations are among the most significant genetic risk factors for developing late onset Parkinson’s disease (PD). To understand whether a therapeutic can modulate LRRK2 levels as a potential disease modifying strategy, it is important to have methods in place to measure the protein with high sensitivity and spec...
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Quantitative Measurements of LRRK2 in Human Cerebrospinal Fluid Demonstrates Increased Levels in G2019S Patients
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TN_cdi_doaj_primary_oai_doaj_org_article_ef89683459a042f5879b192b38d66c89
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_ef89683459a042f5879b192b38d66c89
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1662-453X,1662-4548
E-ISSN
1662-453X
DOI
10.3389/fnins.2020.00526