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Quantitative Measurements of LRRK2 in Human Cerebrospinal Fluid Demonstrates Increased Levels in G20...

Quantitative Measurements of LRRK2 in Human Cerebrospinal Fluid Demonstrates Increased Levels in G20...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_ef89683459a042f5879b192b38d66c89

Quantitative Measurements of LRRK2 in Human Cerebrospinal Fluid Demonstrates Increased Levels in G2019S Patients

About this item

Full title

Quantitative Measurements of LRRK2 in Human Cerebrospinal Fluid Demonstrates Increased Levels in G2019S Patients

Publisher

Lausanne: Frontiers Research Foundation

Journal title

Frontiers in neuroscience, 2020-05, Vol.14, p.526-526

Language

English

Formats

Publication information

Publisher

Lausanne: Frontiers Research Foundation

More information

Scope and Contents

Contents

Leucine-rich repeat kinase 2 (LRRK2) mutations are among the most significant genetic risk factors for developing late onset Parkinson’s disease (PD). To understand whether a therapeutic can modulate LRRK2 levels as a potential disease modifying strategy, it is important to have methods in place to measure the protein with high sensitivity and spec...

Alternative Titles

Full title

Quantitative Measurements of LRRK2 in Human Cerebrospinal Fluid Demonstrates Increased Levels in G2019S Patients

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_ef89683459a042f5879b192b38d66c89

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_ef89683459a042f5879b192b38d66c89

Other Identifiers

ISSN

1662-453X,1662-4548

E-ISSN

1662-453X

DOI

10.3389/fnins.2020.00526

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