High-resolution bioelectrical imaging of Aβ-induced network dysfunction on CMOS-MEAs for neurotoxici...
High-resolution bioelectrical imaging of Aβ-induced network dysfunction on CMOS-MEAs for neurotoxicity and rescue studies
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London: Nature Publishing Group UK
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English
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London: Nature Publishing Group UK
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Neurotoxicity and the accumulation of extracellular amyloid-beta
1–42
(Aβ) peptides are associated with the development of Alzheimer’s disease (AD) and correlate with neuronal activity and network dysfunctions, ultimately leading to cellular death. However, research on neurodegenerative diseases is hampered by the paucity of reliable readouts...
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High-resolution bioelectrical imaging of Aβ-induced network dysfunction on CMOS-MEAs for neurotoxicity and rescue studies
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TN_cdi_doaj_primary_oai_doaj_org_article_f0371022d000406bb4cc62055fe95634
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_f0371022d000406bb4cc62055fe95634
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ISSN
2045-2322
E-ISSN
2045-2322
DOI
10.1038/s41598-017-02635-x