Exosomal cell-to-cell transmission of alpha synuclein oligomers
Exosomal cell-to-cell transmission of alpha synuclein oligomers
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England: BioMed Central Ltd
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English
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England: BioMed Central Ltd
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Aggregation of alpha-synuclein (αsyn) and resulting cytotoxicity is a hallmark of sporadic and familial Parkinson's disease (PD) as well as dementia with Lewy bodies, with recent evidence implicating oligomeric and pre-fibrillar forms of αsyn as the pathogenic species. Recent in vitro studies support the idea of transcellular spread of extracellula...
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Exosomal cell-to-cell transmission of alpha synuclein oligomers
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TN_cdi_doaj_primary_oai_doaj_org_article_f0d46049e50c4f0abe868141b2309e49
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_f0d46049e50c4f0abe868141b2309e49
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ISSN
1750-1326
E-ISSN
1750-1326
DOI
10.1186/1750-1326-7-42