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Exosomal cell-to-cell transmission of alpha synuclein oligomers

Exosomal cell-to-cell transmission of alpha synuclein oligomers

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_f0d46049e50c4f0abe868141b2309e49

Exosomal cell-to-cell transmission of alpha synuclein oligomers

About this item

Full title

Exosomal cell-to-cell transmission of alpha synuclein oligomers

Publisher

England: BioMed Central Ltd

Journal title

Molecular neurodegeneration, 2012-08, Vol.7 (1), p.42-42, Article 42

Language

English

Formats

Publication information

Publisher

England: BioMed Central Ltd

More information

Scope and Contents

Contents

Aggregation of alpha-synuclein (αsyn) and resulting cytotoxicity is a hallmark of sporadic and familial Parkinson's disease (PD) as well as dementia with Lewy bodies, with recent evidence implicating oligomeric and pre-fibrillar forms of αsyn as the pathogenic species. Recent in vitro studies support the idea of transcellular spread of extracellula...

Alternative Titles

Full title

Exosomal cell-to-cell transmission of alpha synuclein oligomers

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_f0d46049e50c4f0abe868141b2309e49

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_f0d46049e50c4f0abe868141b2309e49

Other Identifiers

ISSN

1750-1326

E-ISSN

1750-1326

DOI

10.1186/1750-1326-7-42

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