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Release and uptake of pathologic alpha-synuclein
Author / Creator:Grozdanov, Veselin ; Danzer, Karin M.
Publisher:Berlin/Heidelberg: Springer Berlin Heidelberg
Journal title:Cell and tissue research, 2018-07, Vol.373 (1), p.175-182
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Exosomal cell-to-cell transmission of alpha synuclein oligomers
Author / Creator:Danzer, Karin M ; Kranich, Lisa R ; Ruf, Wolfgang P ; Cagsal-Getkin, Ozge ; Winslow, Ashley R ; Zhu, Liya ; Vanderburg, Charles R ; McLean, Pamela J
Publisher:England: BioMed Central Ltd
Journal title:Molecular neurodegeneration, 2012-08, Vol.7 (1), p.42-42, Article 42
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Systematic comparison of the effects of Alpha-synuclein mutations on its oligomerization and aggregation
Author / Creator:Lázaro, Diana F. ; Rodrigues, Eva F. ; Langohr, Ramona ; Shahpasandzadeh, Hedieh ; Ribeiro, Thales ; Guerreiro, Patrícia ; Gerhardt, Ellen ; Kröhnert, Katharina ; Klucken, Jochen ; Pereira, Marcos D. ; Popova, Blagovesta ; Kruse, Niels ; Mollenhauer, Brit ; Rizzoli, Silvio O. ; Braus, Gerhard H. ; Danzer, Karin M. ; Outeiro, Tiago
Publisher:United States: PLOS
Journal title:PLoS genetics, 2014-11, Vol.10 (11), p.e1004741
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Inflammatory dysregulation of blood monocytes in Parkinson’s disease patients
Author / Creator:Grozdanov, Veselin ; Bliederhaeuser, Corinna ; Ruf, Wolfgang P. ; Roth, Valerie ; Fundel-Clemens, Kathrin ; Zondler, Lisa ; Brenner, David ; Martin-Villalba, Ana ; Hengerer, Bastian ; Kassubek, Jan ; Ludolph, Albert C. ; Weishaupt, Jochen H. ; Danzer, Karin M.
Publisher:Berlin/Heidelberg: Springer Berlin Heidelberg
Journal title:Acta neuropathologica, 2014-11, Vol.128 (5), p.651-663
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Stress induced TDP-43 mobility loss independent of stress granules
Author / Creator:Streit, Lisa ; Kuhn, Timo ; Vomhof, Thomas ; Bopp, Verena ; Ludolph, Albert C. ; Weishaupt, Jochen H. ; Gebhardt, J. Christof M. ; Michaelis, Jens ; Danzer, Karin M.
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2022-09, Vol.13 (1), p.5480-5480, Article 5480
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T-cell dysregulation is associated with disease severity in Parkinson’s Disease
Author / Creator:Bhatia, Divisha ; Grozdanov, Veselin ; Ruf, Wolfgang P. ; Kassubek, Jan ; Ludolph, Albert C. ; Weishaupt, Jochen H. ; Danzer, Karin M.
Publisher:England: BioMed Central Ltd
Journal title:Journal of neuroinflammation, 2021-10, Vol.18 (1), p.250-250, Article 250
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Proteasome impairment by α-synuclein
Author / Creator:Zondler, Lisa ; Kostka, Marcus ; Garidel, Patrick ; Heinzelmann, Udo ; Hengerer, Bastian ; Mayer, Benjamin ; Weishaupt, Jochen H. ; Gillardon, Frank ; Danzer, Karin M.
Publisher:United States: Public Library of Science
Journal title:PloS one, 2017-09, Vol.12 (9), p.e0184040-e0184040
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Peripheral monocytes are functionally altered and invade the CNS in ALS patients
Author / Creator:Zondler, Lisa ; Müller, Kathrin ; Khalaji, Samira ; Bliederhäuser, Corinna ; Ruf, Wolfgang P. ; Grozdanov, Veselin ; Thiemann, Meinolf ; Fundel-Clemes, Katrin ; Freischmidt, Axel ; Holzmann, Karlheinz ; Strobel, Benjamin ; Weydt, Patrick ; Witting, Anke ; Thal, Dietmar R. ; Helferich, Anika M. ; Hengerer, Bastian ; Gottschalk, Kay-Eberhard ; Hill, Oliver ; Kluge, Michael ; Ludolph, Albert C. ; Danzer, Karin M. ; Weishaupt, Jochen H.
Publisher:Berlin/Heidelberg: Springer Berlin Heidelberg
Journal title:Acta neuropathologica, 2016-09, Vol.132 (3), p.391-411
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α-Synuclein fibrils enhance HIV-1 infection of human T cells, macrophages and microglia
Author / Creator:Olari, Lia-Raluca ; Liu, Sichen ; Arnold, Franziska ; Kühlwein, Julia ; Gil Miró, Marta ; Updahaya, Ajeet Rijal ; Stürzel, Christina ; Thal, Dietmar Rudolf ; Walther, Paul ; Sparrer, Konstantin M. J. ; Danzer, Karin M. ; Münch, Jan ; Kirchhoff, Frank
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2025-01, Vol.16 (1), p.813-18, Article 813
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Impaired ATF3 signaling involves SNAP25 in SOD1 mutant ALS patients
Author / Creator:Yazar, Volkan ; Kühlwein, Julia K. ; Knehr, Antje ; Grozdanov, Veselin ; Ekici, Arif B. ; Ludolph, Albert C. ; Danzer, Karin M.
Publisher:London: Nature Publishing Group UK
Journal title:Scientific reports, 2023-07, Vol.13 (1), p.12019-12019, Article 12019
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Mitochondrial genome study in blood of maternally inherited ALS cases
Author / Creator:Brockmann, Sarah J. ; Buck, Eva ; Casoli, Tiziana ; Meirelles, João L. ; Ruf, Wolfgang P. ; Fabbietti, Paolo ; Holzmann, Karlheinz ; Weishaupt, Jochen H. ; Ludolph, Albert C. ; Conti, Fiorenzo ; Danzer, Karin M.
Publisher:England: BioMed Central
Journal title:Human genomics, 2023-07, Vol.17 (1), p.70-70, Article 70
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Chronic Treatment with Novel Small Molecule Hsp90 Inhibitors Rescues Striatal Dopamine Levels but Not α-Synuclein-Induced Neuronal Cell Loss
Author / Creator:McFarland, Nikolaus R. ; Dimant, Hemi ; Kibuuka, Laura ; Ebrahimi-Fakhari, Darius ; Desjardins, Cody A. ; Danzer, Karin M. ; Danzer, Michael ; Fan, Zhanyun ; Schwarzschild, Michael A. ; Hirst, Warren ; McLean, Pamela J.
Publisher:United States: Public Library of Science
Journal title:PloS one, 2014, Vol.9 (1), p.e86048-e86048
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ArticlesPeer ReviewedFull Text
The Golgi-Localized γ-Ear-Containing ARF-Binding (GGA) Proteins Alter Amyloid-β Precursor Protein (APP) Processing through Interaction of Their GAE Domain with the Beta-Site APP Cleaving Enzyme 1 (BAC...
Author / Creator:von Einem, Bjoern ; Wahler, Anke ; Schips, Tobias ; Serrano-Pozo, Alberto ; Proepper, Christian ; Boeckers, Tobias M. ; Rueck, Angelika ; Wirth, Thomas ; Hyman, Bradley T. ; Danzer, Karin M. ; Thal, Dietmar R. ; von Arnim, Christine A. F.
Publisher:United States: Public Library of Science
Journal title:PloS one, 2015-06, Vol.10 (6), p.e0129047-e0129047
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Protein Binding Partners of Dysregulated miRNAs in Parkinson’s Disease Serum
Author / Creator:Ruf, Wolfgang P. ; Freischmidt, Axel ; Grozdanov, Veselin ; Roth, Valerie ; Brockmann, Sarah J. ; Mollenhauer, Brit ; Martin, Dorothea ; Haslinger, Bernhard ; Fundel-Clemens, Katrin ; Otto, Markus ; Arnim, Christine von ; Holzmann, Karlheinz ; Ludolph, Albert C. ; Weishaupt, Jochen H. ; Danzer, Karin M.
Publisher:Switzerland: MDPI AG
Journal title:Cells (Basel, Switzerland), 2021-04, Vol.10 (4), p.791
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LRRK2 contributes to monocyte dysregulation in Parkinson’s disease
Author / Creator:Bliederhaeuser, Corinna ; Zondler, Lisa ; Grozdanov, Veselin ; Ruf, Wolfgang P. ; Brenner, David ; Melrose, Heather L. ; Bauer, Peter ; Ludolph, Albert C. ; Gillardon, Frank ; Kassubek, Jan ; Weishaupt, Jochen H. ; Danzer, Karin M.
Publisher:England: BioMed Central Ltd
Journal title:Acta neuropathologica communications, 2016-11, Vol.4 (1), p.123-123, Article 123
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Age-dependent defects of alpha-synuclein oligomer uptake in microglia and monocytes
Author / Creator:Bliederhaeuser, Corinna ; Grozdanov, Veselin ; Speidel, Anna ; Zondler, Lisa ; Ruf, Wolfgang P. ; Bayer, Hanna ; Kiechle, Martin ; Feiler, Marisa S. ; Freischmidt, Axel ; Brenner, David ; Witting, Anke ; Hengerer, Bastian ; Fändrich, Marcus ; Ludolph, Albert C. ; Weishaupt, Jochen H. ; Gillardon, Frank ; Danzer, Karin M.
Publisher:Berlin/Heidelberg: Springer Berlin Heidelberg
Journal title:Acta neuropathologica, 2016-03, Vol.131 (3), p.379-391
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Extracellular vesicle sorting of α-Synuclein is regulated by sumoylation
Author / Creator:Kunadt, Marcel ; Eckermann, Katrin ; Stuendl, Anne ; Gong, Jing ; Russo, Belisa ; Strauss, Katrin ; Rai, Surya ; Kügler, Sebastian ; Falomir Lockhart, Lisandro ; Schwalbe, Martin ; Krumova, Petranka ; Oliveira, Luis M. A. ; Bähr, Mathias ; Möbius, Wiebke ; Levin, Johannes ; Giese, Armin ; Kruse, Niels ; Mollenhauer, Brit ; Geiss-Friedlander, Ruth ; Ludolph, Albert C. ; Freischmidt, Axel ; Feiler, Marisa S. ; Danzer, Karin M. ; Zweckstetter, Markus ; Jovin, Thomas M. ; Simons, Mikael ; Weishaupt, Jochen H. ; Schneider, Anja
Publisher:Berlin/Heidelberg: Springer Berlin Heidelberg
Journal title:Acta neuropathologica, 2015-05, Vol.129 (5), p.695-713
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[alpha]-Synuclein in Parkinson's Disease: Pathogenic Function and Translation into Animal Models
Author / Creator:Eschbach, Judith ; Danzer, Karin M
Publisher:Basel: S. Karger AG
Journal title:Neuro-degenerative diseases, 2014-06, Vol.14 (1), p.1-17
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High Agreement Across Laboratories Between Different Alpha‐Synuclein Seed Amplification Protocols
Author / Creator:Bräuer, Stefan ; Weber, Maximilian ; Deuschle, Christian ; Julia, Kühlwein ; Concha‐Marambio, Luis ; Bernhardt, Alexander M. ; Kadam, Vaibhavi ; Mengel, David ; Ruf, Wolfgang P. ; Kassubek, Jan ; Schniewind, Iñaki ; Kuhs, Sandra ; Rossi, Marcello ; Parchi, Piero ; Levin, Johannes ; Danzer, Karin M. ; Synofzik, Matthis ; Brockmann, Kathrin ; Falkenburger, Björn H.
Publisher:England: John Wiley & Sons, Inc
Journal title:European journal of neurology, 2025-04, Vol.32 (4), p.e70165-n/a
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Dysregulation of a novel miR-1825/TBCB/TUBA4A pathway in sporadic and familial ALS
Author / Creator:Helferich, Anika M. ; Brockmann, Sarah J. ; Reinders, Jörg ; Deshpande, Dhruva ; Holzmann, Karlheinz ; Brenner, David ; Andersen, Peter M. ; Petri, Susanne ; Thal, Dietmar R. ; Michaelis, Jens ; Otto, Markus ; Just, Steffen ; Ludolph, Albert C. ; Danzer, Karin M. ; Freischmidt, Axel ; Weishaupt, Jochen H.
Publisher:Cham: Springer International Publishing
Journal title:Cellular and molecular life sciences : CMLS, 2018-12, Vol.75 (23), p.4301-4319
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Release and uptake of pathologic alpha-synuclein

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Exosomal cell-to-cell transmission of alpha synuclein oligomers

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Systematic comparison of the effects of Alpha-synuclein mutations on its oligomerization and aggregation

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Inflammatory dysregulation of blood monocytes in Parkinson’s disease patients

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Stress induced TDP-43 mobility loss independent of stress granules

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T-cell dysregulation is associated with disease severity in Parkinson’s Disease

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Proteasome impairment by α-synuclein

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Peripheral monocytes are functionally altered and invade the CNS in ALS patients

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α-Synuclein fibrils enhance HIV-1 infection of human T cells, macrophages and microglia

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Impaired ATF3 signaling involves SNAP25 in SOD1 mutant ALS patients

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Mitochondrial genome study in blood of maternally inherited ALS cases

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Chronic Treatment with Novel Small Molecule Hsp90 Inhibitors Rescues Striatal Dopamine Levels but Not α-Synuclein-Induced Neuronal Cell Loss

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The Golgi-Localized γ-Ear-Containing ARF-Binding (GGA) Proteins Alter Amyloid-β Precursor Protein (APP) Processing through Interaction of Their GAE Domain with the Beta-Site APP Cleaving Enzyme 1 (BAC...

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Protein Binding Partners of Dysregulated miRNAs in Parkinson’s Disease Serum

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LRRK2 contributes to monocyte dysregulation in Parkinson’s disease

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Age-dependent defects of alpha-synuclein oligomer uptake in microglia and monocytes

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Extracellular vesicle sorting of α-Synuclein is regulated by sumoylation

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[alpha]-Synuclein in Parkinson's Disease: Pathogenic Function and Translation into Animal Models

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High Agreement Across Laboratories Between Different Alpha‐Synuclein Seed Amplification Protocols

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Dysregulation of a novel miR-1825/TBCB/TUBA4A pathway in sporadic and familial ALS

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