P-tau subgroups in AD relate to distinct amyloid production and synaptic integrity profiles
P-tau subgroups in AD relate to distinct amyloid production and synaptic integrity profiles
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England: BioMed Central Ltd
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English
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England: BioMed Central Ltd
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We previously identified four Alzheimer's disease (AD) subgroups with increasingly higher cerebrospinal fluid (CSF) levels of tau phosphorylated at threonine 181 (p-tau). These subgroups included individuals across the cognitive spectrum, suggesting p-tau subgroups could reflect distinct biological changes in AD, rather than disease severity. There...
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P-tau subgroups in AD relate to distinct amyloid production and synaptic integrity profiles
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TN_cdi_doaj_primary_oai_doaj_org_article_f115a77421a641c79c0c23bf303043a8
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_f115a77421a641c79c0c23bf303043a8
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ISSN
1758-9193
E-ISSN
1758-9193
DOI
10.1186/s13195-022-01038-z