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P-tau subgroups in AD relate to distinct amyloid production and synaptic integrity profiles

P-tau subgroups in AD relate to distinct amyloid production and synaptic integrity profiles

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_f115a77421a641c79c0c23bf303043a8

P-tau subgroups in AD relate to distinct amyloid production and synaptic integrity profiles

About this item

Full title

P-tau subgroups in AD relate to distinct amyloid production and synaptic integrity profiles

Publisher

England: BioMed Central Ltd

Journal title

Alzheimer's research & therapy, 2022-07, Vol.14 (1), p.95-95, Article 95

Language

English

Formats

Publication information

Publisher

England: BioMed Central Ltd

More information

Scope and Contents

Contents

We previously identified four Alzheimer's disease (AD) subgroups with increasingly higher cerebrospinal fluid (CSF) levels of tau phosphorylated at threonine 181 (p-tau). These subgroups included individuals across the cognitive spectrum, suggesting p-tau subgroups could reflect distinct biological changes in AD, rather than disease severity. There...

Alternative Titles

Full title

P-tau subgroups in AD relate to distinct amyloid production and synaptic integrity profiles

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_f115a77421a641c79c0c23bf303043a8

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_f115a77421a641c79c0c23bf303043a8

Other Identifiers

ISSN

1758-9193

E-ISSN

1758-9193

DOI

10.1186/s13195-022-01038-z

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