Single‐cell and spatial transcriptomics reveal POSTN+ cancer‐associated fibroblasts correlated with...
Single‐cell and spatial transcriptomics reveal POSTN+ cancer‐associated fibroblasts correlated with immune suppression and tumour progression in non‐small cell lung cancer
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Author / Creator
Chen, Chao , Guo, Qiang , Liu, Yang , Hou, Qinghua , Liao, Mengying , Guo, Yanying , Zang, Yupeng , Wang, Fei , Liu, Huanyu , Luan, Xinyu , Liang, Yanling , Guan, Zhuojue , Li, Yanling , Liu, Haozhen , Dong, Xuan , Zhang, Xiuqing , Liu, Jixian and Xu, Qumiao
Publisher
United States: John Wiley & Sons, Inc
Journal title
Language
English
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Publication information
Publisher
United States: John Wiley & Sons, Inc
Subjects
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Scope and Contents
Contents
Background
Cancer‐associated fibroblasts (CAFs) are potential targets for cancer therapy. Due to the heterogeneity of CAFs, the influence of CAF subpopulations on the progression of lung cancer is still unclear, which impedes the translational advances in targeting CAFs.
Methods
We performed single‐cell RNA sequencing (scRNA‐seq) on tumour...
Alternative Titles
Full title
Single‐cell and spatial transcriptomics reveal POSTN+ cancer‐associated fibroblasts correlated with immune suppression and tumour progression in non‐small cell lung cancer
Authors, Artists and Contributors
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Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_f14e3806c20349b3b808f43651e02f33
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_f14e3806c20349b3b808f43651e02f33
Other Identifiers
ISSN
2001-1326
E-ISSN
2001-1326
DOI
10.1002/ctm2.1515