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Single‐cell and spatial transcriptomics reveal POSTN+ cancer‐associated fibroblasts correlated with...

Single‐cell and spatial transcriptomics reveal POSTN+ cancer‐associated fibroblasts correlated with...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_f14e3806c20349b3b808f43651e02f33

Single‐cell and spatial transcriptomics reveal POSTN+ cancer‐associated fibroblasts correlated with immune suppression and tumour progression in non‐small cell lung cancer

About this item

Full title

Single‐cell and spatial transcriptomics reveal POSTN+ cancer‐associated fibroblasts correlated with immune suppression and tumour progression in non‐small cell lung cancer

Publisher

United States: John Wiley & Sons, Inc

Journal title

Clinical and Translational Medicine, 2023-12, Vol.13 (12), p.e1515-n/a

Language

English

Formats

Publication information

Publisher

United States: John Wiley & Sons, Inc

More information

Scope and Contents

Contents

Background
Cancer‐associated fibroblasts (CAFs) are potential targets for cancer therapy. Due to the heterogeneity of CAFs, the influence of CAF subpopulations on the progression of lung cancer is still unclear, which impedes the translational advances in targeting CAFs.
Methods
We performed single‐cell RNA sequencing (scRNA‐seq) on tumour...

Alternative Titles

Full title

Single‐cell and spatial transcriptomics reveal POSTN+ cancer‐associated fibroblasts correlated with immune suppression and tumour progression in non‐small cell lung cancer

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_f14e3806c20349b3b808f43651e02f33

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_f14e3806c20349b3b808f43651e02f33

Other Identifiers

ISSN

2001-1326

E-ISSN

2001-1326

DOI

10.1002/ctm2.1515

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