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Toxoplasma gondii α‐amylase deletion mutant is a promising vaccine against acute and chronic toxopla...

Toxoplasma gondii α‐amylase deletion mutant is a promising vaccine against acute and chronic toxopla...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_f18a8af525e748189d4d52cb58624c00

Toxoplasma gondii α‐amylase deletion mutant is a promising vaccine against acute and chronic toxoplasmosis

About this item

Full title

Toxoplasma gondii α‐amylase deletion mutant is a promising vaccine against acute and chronic toxoplasmosis

Publisher

United States: John Wiley & Sons, Inc

Journal title

Microbial biotechnology, 2020-11, Vol.13 (6), p.2057-2069

Language

English

Formats

Publication information

Publisher

United States: John Wiley & Sons, Inc

More information

Scope and Contents

Contents

In the study, we first generated a ME49Δα‐amy mutant and discovered that loss of α‐AMY robustly grew in vitro but contributed to significant virulence attenuation in vivo. The results obtained from our study revealed that ME49Δα‐amy attenuated strain could provide efficient protection against acute infection and chronic infection caused by multiple...

Alternative Titles

Full title

Toxoplasma gondii α‐amylase deletion mutant is a promising vaccine against acute and chronic toxoplasmosis

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_f18a8af525e748189d4d52cb58624c00

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_f18a8af525e748189d4d52cb58624c00

Other Identifiers

ISSN

1751-7915

E-ISSN

1751-7915

DOI

10.1111/1751-7915.13668

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