Toxoplasma gondii α‐amylase deletion mutant is a promising vaccine against acute and chronic toxopla...
Toxoplasma gondii α‐amylase deletion mutant is a promising vaccine against acute and chronic toxoplasmosis
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Author / Creator
Yang, Jing , Yang, Chenghang , Qian, Jiahui , Li, Facai , Zhao, Junlong and Fang, Rui
Publisher
United States: John Wiley & Sons, Inc
Journal title
Language
English
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Publication information
Publisher
United States: John Wiley & Sons, Inc
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Scope and Contents
Contents
In the study, we first generated a ME49Δα‐amy mutant and discovered that loss of α‐AMY robustly grew in vitro but contributed to significant virulence attenuation in vivo. The results obtained from our study revealed that ME49Δα‐amy attenuated strain could provide efficient protection against acute infection and chronic infection caused by multiple...
Alternative Titles
Full title
Toxoplasma gondii α‐amylase deletion mutant is a promising vaccine against acute and chronic toxoplasmosis
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Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_f18a8af525e748189d4d52cb58624c00
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_f18a8af525e748189d4d52cb58624c00
Other Identifiers
ISSN
1751-7915
E-ISSN
1751-7915
DOI
10.1111/1751-7915.13668