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Exploring the alternative virulence determinants PB2 S155N and PA S49Y/D347G that promote mammalian...

Exploring the alternative virulence determinants PB2 S155N and PA S49Y/D347G that promote mammalian...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_f1d7b5d412ff41e291084e4a0210690e

Exploring the alternative virulence determinants PB2 S155N and PA S49Y/D347G that promote mammalian adaptation of the H9N2 avian influenza virus in mice

About this item

Full title

Exploring the alternative virulence determinants PB2 S155N and PA S49Y/D347G that promote mammalian adaptation of the H9N2 avian influenza virus in mice

Publisher

England: BioMed Central Ltd

Journal title

Veterinary research (Paris), 2023-10, Vol.54 (1), p.97-97, Article 97

Language

English

Formats

Publication information

Publisher

England: BioMed Central Ltd

More information

Scope and Contents

Contents

The occurrence of human infections caused by avian H9N2 influenza viruses has raised concerns regarding the potential for human epidemics and pandemics. The molecular basis of viral adaptation to a new host needs to be further studied. Here, the bases of nucleotides 627 and 701 of PB2 were changed according to the uncoverable purine-to-pyrimidine t...

Alternative Titles

Full title

Exploring the alternative virulence determinants PB2 S155N and PA S49Y/D347G that promote mammalian adaptation of the H9N2 avian influenza virus in mice

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_f1d7b5d412ff41e291084e4a0210690e

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_f1d7b5d412ff41e291084e4a0210690e

Other Identifiers

ISSN

1297-9716,0928-4249

E-ISSN

1297-9716

DOI

10.1186/s13567-023-01221-6

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