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The CD2 isoform of protocadherin‐15 is an essential component of the tip‐link complex in mature audi...

The CD2 isoform of protocadherin‐15 is an essential component of the tip‐link complex in mature audi...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_f2013a19a5074312834258fa88eb41b3

The CD2 isoform of protocadherin‐15 is an essential component of the tip‐link complex in mature auditory hair cells

About this item

Full title

The CD2 isoform of protocadherin‐15 is an essential component of the tip‐link complex in mature auditory hair cells

Publisher

London: Nature Publishing Group UK

Journal title

EMBO molecular medicine, 2014-07, Vol.6 (7), p.984-992

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

Protocadherin‐15 (Pcdh15) is a component of the tip‐links, the extracellular filaments that gate hair cell mechano‐electrical transduction channels in the inner ear. There are three Pcdh15 splice isoforms (CD1, CD2 and CD3), which only differ by their cytoplasmic domains; they are thought to function redundantly in mechano‐electrical transduction d...

Alternative Titles

Full title

The CD2 isoform of protocadherin‐15 is an essential component of the tip‐link complex in mature auditory hair cells

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_f2013a19a5074312834258fa88eb41b3

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_f2013a19a5074312834258fa88eb41b3

Other Identifiers

ISSN

1757-4676,1757-4684

E-ISSN

1757-4684

DOI

10.15252/emmm.201403976

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