Cryo-EM structure of translesion DNA synthesis polymerase ζ with a base pair mismatch
Cryo-EM structure of translesion DNA synthesis polymerase ζ with a base pair mismatch
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London: Nature Publishing Group UK
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Language
English
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London: Nature Publishing Group UK
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The B-family multi-subunit DNA polymerase ζ (Polζ) is important for translesion DNA synthesis (TLS) during replication, due to its ability to extend synthesis past nucleotides opposite DNA lesions and mismatched base pairs. We present a cryo-EM structure of
Saccharomyces cerevisiae
Polζ with an A:C mismatch at the primer terminus. The structu...
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Full title
Cryo-EM structure of translesion DNA synthesis polymerase ζ with a base pair mismatch
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TN_cdi_doaj_primary_oai_doaj_org_article_f26c65399068427e98751e9f37644e54
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_f26c65399068427e98751e9f37644e54
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ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-022-28644-7
