Genetic regulatory effects modified by immune activation contribute to autoimmune disease associatio...
Genetic regulatory effects modified by immune activation contribute to autoimmune disease associations
About this item
Full title
Author / Creator
Kim-Hellmuth, Sarah , Bechheim, Matthias , Pütz, Benno , Mohammadi, Pejman , Nédélec, Yohann , Giangreco, Nicholas , Becker, Jessica , Kaiser, Vera , Fricker, Nadine , Beier, Esther , Boor, Peter , Castel, Stephane E. , Nöthen, Markus M. , Barreiro, Luis B. , Pickrell, Joseph K. , Müller-Myhsok, Bertram , Lappalainen, Tuuli , Schumacher, Johannes and Hornung, Veit
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
Formats
Publication information
Publisher
London: Nature Publishing Group UK
Subjects
More information
Scope and Contents
Contents
The immune system plays a major role in human health and disease, and understanding genetic causes of interindividual variability of immune responses is vital. Here, we isolate monocytes from 134 genotyped individuals, stimulate these cells with three defined microbe-associated molecular patterns (LPS, MDP, and 5′-ppp-dsRNA), and profile the transc...
Alternative Titles
Full title
Genetic regulatory effects modified by immune activation contribute to autoimmune disease associations
Authors, Artists and Contributors
Author / Creator
Bechheim, Matthias
Pütz, Benno
Mohammadi, Pejman
Nédélec, Yohann
Giangreco, Nicholas
Becker, Jessica
Kaiser, Vera
Fricker, Nadine
Beier, Esther
Boor, Peter
Castel, Stephane E.
Nöthen, Markus M.
Barreiro, Luis B.
Pickrell, Joseph K.
Müller-Myhsok, Bertram
Lappalainen, Tuuli
Schumacher, Johannes
Hornung, Veit
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_f274c977e16349e182f563f89ede2112
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_f274c977e16349e182f563f89ede2112
Other Identifiers
ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-017-00366-1
