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Phagosomal signalling of the C-type lectin receptor Dectin-1 is terminated by intramembrane proteoly...

Phagosomal signalling of the C-type lectin receptor Dectin-1 is terminated by intramembrane proteoly...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_f2acefb3574e4b9da6fd801ea20dcfc5

Phagosomal signalling of the C-type lectin receptor Dectin-1 is terminated by intramembrane proteolysis

About this item

Full title

Phagosomal signalling of the C-type lectin receptor Dectin-1 is terminated by intramembrane proteolysis

Publisher

London: Nature Publishing Group UK

Journal title

Nature communications, 2022-04, Vol.13 (1), p.1880-1880, Article 1880

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

Sensing of pathogens by pattern recognition receptors (PRR) is critical to initiate protective host defence reactions. However, activation of the immune system has to be carefully titrated to avoid tissue damage necessitating mechanisms to control and terminate PRR signalling. Dectin-1 is a PRR for fungal β-glucans on immune cells that is rapidly i...

Alternative Titles

Full title

Phagosomal signalling of the C-type lectin receptor Dectin-1 is terminated by intramembrane proteolysis

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_f2acefb3574e4b9da6fd801ea20dcfc5

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_f2acefb3574e4b9da6fd801ea20dcfc5

Other Identifiers

ISSN

2041-1723

E-ISSN

2041-1723

DOI

10.1038/s41467-022-29474-3

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