Phagosomal signalling of the C-type lectin receptor Dectin-1 is terminated by intramembrane proteoly...
Phagosomal signalling of the C-type lectin receptor Dectin-1 is terminated by intramembrane proteolysis
About this item
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Author / Creator
Mentrup, Torben , Stumpff-Niggemann, Anna Yamina , Leinung, Nadja , Schlosser, Christine , Schubert, Katja , Wehner, Rebekka , Tunger, Antje , Schatz, Valentin , Neubert, Patrick , Gradtke, Ann-Christine , Wolf, Janina , Rose-John, Stefan , Saftig, Paul , Dalpke, Alexander , Jantsch, Jonathan , Schmitz, Marc , Fluhrer, Regina , Jacobsen, Ilse D. and Schröder, Bernd
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
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Publication information
Publisher
London: Nature Publishing Group UK
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More information
Scope and Contents
Contents
Sensing of pathogens by pattern recognition receptors (PRR) is critical to initiate protective host defence reactions. However, activation of the immune system has to be carefully titrated to avoid tissue damage necessitating mechanisms to control and terminate PRR signalling. Dectin-1 is a PRR for fungal β-glucans on immune cells that is rapidly i...
Alternative Titles
Full title
Phagosomal signalling of the C-type lectin receptor Dectin-1 is terminated by intramembrane proteolysis
Authors, Artists and Contributors
Author / Creator
Stumpff-Niggemann, Anna Yamina
Leinung, Nadja
Schlosser, Christine
Schubert, Katja
Wehner, Rebekka
Tunger, Antje
Schatz, Valentin
Neubert, Patrick
Gradtke, Ann-Christine
Wolf, Janina
Rose-John, Stefan
Saftig, Paul
Dalpke, Alexander
Jantsch, Jonathan
Schmitz, Marc
Fluhrer, Regina
Jacobsen, Ilse D.
Schröder, Bernd
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_f2acefb3574e4b9da6fd801ea20dcfc5
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_f2acefb3574e4b9da6fd801ea20dcfc5
Other Identifiers
ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-022-29474-3