Structural basis of protein condensation on microtubules underlying branching microtubule nucleation
Structural basis of protein condensation on microtubules underlying branching microtubule nucleation
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London: Nature Publishing Group UK
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English
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London: Nature Publishing Group UK
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Targeting protein for Xklp2 (TPX2) is a key factor that stimulates branching microtubule nucleation during cell division. Upon binding to microtubules (MTs), TPX2 forms condensates via liquid-liquid phase separation, which facilitates recruitment of microtubule nucleation factors and tubulin. We report the structure of the TPX2 C-terminal minimal a...
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Structural basis of protein condensation on microtubules underlying branching microtubule nucleation
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TN_cdi_doaj_primary_oai_doaj_org_article_f312d37cd7eb48f7a1e4ed849c46d150
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_f312d37cd7eb48f7a1e4ed849c46d150
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ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-023-39176-z
