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Maternal SMCHD1 regulates Hox gene expression and patterning in the mouse embryo

Maternal SMCHD1 regulates Hox gene expression and patterning in the mouse embryo

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_f3dd1a6eccaf4f698759ff576571bf98

Maternal SMCHD1 regulates Hox gene expression and patterning in the mouse embryo

About this item

Full title

Maternal SMCHD1 regulates Hox gene expression and patterning in the mouse embryo

Publisher

London: Nature Publishing Group UK

Journal title

Nature communications, 2022-07, Vol.13 (1), p.4295-13, Article 4295

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

Parents transmit genetic and epigenetic information to their offspring. Maternal effect genes regulate the offspring epigenome to ensure normal development. Here we report that the epigenetic regulator SMCHD1 has a maternal effect on
Hox
gene expression and skeletal patterning. Maternal SMCHD1, present in the oocyte and preimplantation embryo...

Alternative Titles

Full title

Maternal SMCHD1 regulates Hox gene expression and patterning in the mouse embryo

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_f3dd1a6eccaf4f698759ff576571bf98

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_f3dd1a6eccaf4f698759ff576571bf98

Other Identifiers

ISSN

2041-1723

E-ISSN

2041-1723

DOI

10.1038/s41467-022-32057-x

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