Maternal SMCHD1 regulates Hox gene expression and patterning in the mouse embryo
Maternal SMCHD1 regulates Hox gene expression and patterning in the mouse embryo
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Publisher
London: Nature Publishing Group UK
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Language
English
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Publisher
London: Nature Publishing Group UK
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Contents
Parents transmit genetic and epigenetic information to their offspring. Maternal effect genes regulate the offspring epigenome to ensure normal development. Here we report that the epigenetic regulator SMCHD1 has a maternal effect on
Hox
gene expression and skeletal patterning. Maternal SMCHD1, present in the oocyte and preimplantation embryo...
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Full title
Maternal SMCHD1 regulates Hox gene expression and patterning in the mouse embryo
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TN_cdi_doaj_primary_oai_doaj_org_article_f3dd1a6eccaf4f698759ff576571bf98
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_f3dd1a6eccaf4f698759ff576571bf98
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ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-022-32057-x