Repurposing the selective estrogen receptor modulator bazedoxifene to suppress gastrointestinal canc...
Repurposing the selective estrogen receptor modulator bazedoxifene to suppress gastrointestinal cancer growth
About this item
Full title
Author / Creator
Thilakasiri, Pathum , Huynh, Jennifer , Poh, Ashleigh R , Tan, Chin Wee , Nero, Tracy L , Tran, Kelly , Parslow, Adam C , Afshar‐Sterle, Shoukat , Baloyan, David , Hannan, Natalie J , Buchert, Michael , Scott, Andrew Mark , Griffin, Michael DW , Hollande, Frederic , Parker, Michael W , Putoczki, Tracy L , Ernst, Matthias and Chand, Ashwini L
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
Formats
Publication information
Publisher
London: Nature Publishing Group UK
Subjects
More information
Scope and Contents
Contents
Excessive signaling through gp130, the shared receptor for the interleukin (IL)6 family of cytokines, is a common hallmark in solid malignancies and promotes their progression. Here, we established the
in vivo
utility of
bazedoxifene,
a steroid analog clinically approved for the treatment of osteoporosis, to suppress gp130‐dependent tum...
Alternative Titles
Full title
Repurposing the selective estrogen receptor modulator bazedoxifene to suppress gastrointestinal cancer growth
Authors, Artists and Contributors
Author / Creator
Huynh, Jennifer
Poh, Ashleigh R
Tan, Chin Wee
Nero, Tracy L
Tran, Kelly
Parslow, Adam C
Afshar‐Sterle, Shoukat
Baloyan, David
Hannan, Natalie J
Buchert, Michael
Scott, Andrew Mark
Griffin, Michael DW
Hollande, Frederic
Parker, Michael W
Putoczki, Tracy L
Ernst, Matthias
Chand, Ashwini L
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_f3ddb855617e4e378193d6b8beddb2bb
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_f3ddb855617e4e378193d6b8beddb2bb
Other Identifiers
ISSN
1757-4676
E-ISSN
1757-4684
DOI
10.15252/emmm.201809539
