Amyloid-beta modulates microglial responses by binding to the triggering receptor expressed on myelo...
Amyloid-beta modulates microglial responses by binding to the triggering receptor expressed on myeloid cells 2 (TREM2)
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Author / Creator
Zhong, Li , Wang, Zongqi , Wang, Daxin , Wang, Zhe , Martens, Yuka A , Wu, Linbei , Xu, Ying , Wang, Kai , Li, Jianguo , Huang, Ruizhi , Can, Dan , Xu, Huaxi , Bu, Guojun and Chen, Xiao-Fen
Publisher
England: BioMed Central
Journal title
Language
English
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Publisher
England: BioMed Central
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Contents
TREM2 is an innate immune receptor specifically expressed in microglia. Coding variations in TREM2 have been reported to increase the risk for Alzheimer's disease (AD) and other neurodegenerative diseases. While multiple studies support a role for TREM2 in microglial recruitment to amyloid plaques, the chemoattractant factor modulating TREM2-depend...
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Full title
Amyloid-beta modulates microglial responses by binding to the triggering receptor expressed on myeloid cells 2 (TREM2)
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Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_f413ba11b8e2416fb1992f25f45c6001
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_f413ba11b8e2416fb1992f25f45c6001
Other Identifiers
ISSN
1750-1326
E-ISSN
1750-1326
DOI
10.1186/s13024-018-0247-7
