Multiplatform analyses reveal distinct drivers of systemic pathogenesis in adult versus pediatric se...
Multiplatform analyses reveal distinct drivers of systemic pathogenesis in adult versus pediatric severe acute COVID-19
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Author / Creator
Druzak, Samuel , Iffrig, Elizabeth , Roberts, Blaine R. , Zhang, Tiantian , Fibben, Kirby S. , Sakurai, Yumiko , Verkerke, Hans P. , Rostad, Christina A. , Chahroudi, Ann , Schneider, Frank , Wong, Andrew Kam Ho , Roberts, Anne M. , Chandler, Joshua D. , Kim, Susan O. , Mosunjac, Mario , Mosunjac, Marina , Geller, Rachel , Albizua, Igor , Stowell, Sean R. , Arthur, Connie M. , Anderson, Evan J. , Ivanova, Anna A. , Ahn, Jun , Liu, Xueyun , Maner-Smith, Kristal , Bowen, Thomas , Paiardini, Mirko , Bosinger, Steve E. , Roback, John D. , Kulpa, Deanna A. , Silvestri, Guido , Lam, Wilbur A. , Ortlund, Eric A. and Maier, Cheryl L.
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
Formats
Publication information
Publisher
London: Nature Publishing Group UK
Subjects
More information
Scope and Contents
Contents
The pathogenesis of multi-organ dysfunction associated with severe acute SARS-CoV-2 infection remains poorly understood. Endothelial damage and microvascular thrombosis have been identified as drivers of COVID-19 severity, yet the mechanisms underlying these processes remain elusive. Here we show alterations in fluid shear stress-responsive pathway...
Alternative Titles
Full title
Multiplatform analyses reveal distinct drivers of systemic pathogenesis in adult versus pediatric severe acute COVID-19
Authors, Artists and Contributors
Author / Creator
Iffrig, Elizabeth
Roberts, Blaine R.
Zhang, Tiantian
Fibben, Kirby S.
Sakurai, Yumiko
Verkerke, Hans P.
Rostad, Christina A.
Chahroudi, Ann
Schneider, Frank
Wong, Andrew Kam Ho
Roberts, Anne M.
Chandler, Joshua D.
Kim, Susan O.
Mosunjac, Mario
Mosunjac, Marina
Geller, Rachel
Albizua, Igor
Stowell, Sean R.
Arthur, Connie M.
Anderson, Evan J.
Ivanova, Anna A.
Ahn, Jun
Liu, Xueyun
Maner-Smith, Kristal
Bowen, Thomas
Paiardini, Mirko
Bosinger, Steve E.
Roback, John D.
Kulpa, Deanna A.
Silvestri, Guido
Lam, Wilbur A.
Ortlund, Eric A.
Maier, Cheryl L.
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_f453c7377ff248be8d16d63d8c87445a
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_f453c7377ff248be8d16d63d8c87445a
Other Identifiers
ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-023-37269-3
