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Paiardini, Mirko
Journal title:American Men & Women of Science : A Biographical Directory of Today’s Leaders in Physical, Biological and Related Sciences: OCO-QIN, 2022, p.8617-8617
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Paiardini, Mirko
Journal title:American Men & Women of Science : A Biographical Directory of Today’s Leaders in Physical, Biological and Related Sciences: OGA-QYA, 2021, p.8589-8589
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ArticlesPeer ReviewedFull Text
Robust and persistent reactivation of SIV and HIV by N-803 and depletion of CD8+ cells
Author / Creator:McBrien, Julia Bergild ; Mavigner, Maud ; Franchitti, Lavinia ; Smith, S. Abigail ; White, Erick ; Tharp, Gregory K. ; Walum, Hasse ; Busman-Sahay, Kathleen ; Aguilera-Sandoval, Christian R. ; Thayer, William O. ; Spagnuolo, Rae Ann ; Kovarova, Martina ; Wahl, Angela ; Cervasi, Barbara ; Margolis, David M. ; Vanderford, Thomas H. ; Carnathan, Diane G. ; Paiardini, Mirko ; Lifson, Jeffrey D. ; Lee, John H. ; Safrit, Jeffrey T. ; Bosinger, Steven E. ; Estes, Jacob D. ; Derdeyn, Cynthia A. ; Garcia, J. Victor ; Kulpa, Deanna A. ; Chahroudi, Ann ; Silvestri, Guido
Publisher:London: Nature Publishing Group UK
Journal title:Nature (London), 2020-02, Vol.578 (7793), p.154-159
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ArticlesPeer ReviewedFull Text
Natural SIV Hosts: Showing AIDS the Door
Author / Creator:Chahroudi, Ann ; Bosinger, Steven E. ; Vanderford, Thomas H. ; Paiardini, Mirko ; Silvestri, Guido
Publisher:Washington, DC: American Association for the Advancement of Science
Journal title:Science (American Association for the Advancement of Science), 2012-03, Vol.335 (6073), p.1188-1193
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IL-21 and IFNα therapy rescues terminally differentiated NK cells and limits SIV reservoir in ART-treated macaques
Author / Creator:Harper, Justin ; Huot, Nicolas ; Micci, Luca ; Tharp, Gregory ; King, Colin ; Rascle, Philippe ; Shenvi, Neeta ; Wang, Hong ; Galardi, Cristin ; Upadhyay, Amit A. ; Villinger, Francois ; Lifson, Jeffrey ; Silvestri, Guido ; Easley, Kirk ; Jacquelin, Beatrice ; Bosinger, Steven ; Müller-Trutwin, Michaela ; Paiardini, Mirko
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2021-05, Vol.12 (1), p.2866-12, Article 2866
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Recommendations for measuring HIV reservoir size in cure-directed clinical trials
Author / Creator:Abdel-Mohsen, Mohamed ; Richman, Douglas ; Siliciano, Robert F. ; Nussenzweig, Michel C. ; Howell, Bonnie J. ; Martinez-Picado, Javier ; Chomont, Nicolas ; Bar, Katharine J. ; Yu, Xu G. ; Lichterfeld, Mathias ; Alcami, Jose ; Hazuda, Daria ; Bushman, Frederic ; Siliciano, Janet D. ; Betts, Michael R. ; Spivak, Adam M. ; Planelles, Vicente ; Hahn, Beatrice H. ; Smith, Davey M. ; Ho, Ya-Chi ; Buzon, Maria J. ; Gaebler, Christian ; Paiardini, Mirko ; Li, Qingsheng ; Estes, Jacob D. ; Hope, Thomas J. ; Kostman, Jay ; Mounzer, Karam ; Caskey, Marina ; Fox, Lawrence ; Frank, Ian ; Riley, James L. ; Tebas, Pablo ; Montaner, Luis J.
Publisher:New York: Nature Publishing Group US
Journal title:Nature medicine, 2020-09, Vol.26 (9), p.1339-1350
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SIV-induced terminally differentiated adaptive NK cells in lymph nodes associated with enhanced MHC-E restricted activity
Author / Creator:Huot, Nicolas ; Rascle, Philippe ; Petitdemange, Caroline ; Contreras, Vanessa ; Stürzel, Christina M. ; Baquero, Eduard ; Harper, Justin L. ; Passaes, Caroline ; Legendre, Rachel ; Varet, Hugo ; Madec, Yoann ; Sauermann, Ulrike ; Stahl-Hennig, Christiane ; Nattermann, Jacob ; Saez-Cirion, Asier ; Le Grand, Roger ; Keith Reeves, R. ; Paiardini, Mirko ; Kirchhoff, Frank ; Jacquelin, Beatrice ; Müller-Trutwin, Michaela
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2021-02, Vol.12 (1), p.1282-1282, Article 1282
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ArticlesPeer ReviewedFull Text
CTLA-4 and PD-1 dual blockade induces SIV reactivation without control of rebound after antiretroviral therapy interruption
Author / Creator:Harper, Justin ; Gordon, Shari ; Chan, Chi Ngai ; Wang, Hong ; Lindemuth, Emily ; Galardi, Cristin ; Falcinelli, Shane D. ; Raines, Samuel L. M. ; Read, Jenna L. ; Nguyen, Kevin ; McGary, Colleen S ; Nekorchuk, Michael ; Busman-Sahay, Kathleen ; Schawalder, James ; King, Colin ; Pino, Maria ; Micci, Luca ; Cervasi, Barbara ; Jean, Sherrie ; Sanderson, Andrew ; Johns, Brian ; Koblansky, A. Alicia ; Amrine-Madsen, Heather ; Lifson, Jeffrey ; Margolis, David M. ; Silvestri, Guido ; Bar, Katharine J. ; Favre, David ; Estes, Jacob D. ; Paiardini, Mirko
Publisher:New York: Nature Publishing Group US
Journal title:Nature medicine, 2020-04, Vol.26 (4), p.519-528
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Innate, non-cytolytic CD8+ T cell-mediated suppression of HIV replication by MHC-independent inhibition of virus transcription
Author / Creator:Zanoni, Michelle ; Palesch, David ; Pinacchio, Claudia ; Statzu, Maura ; Tharp, Gregory K ; Paiardini, Mirko ; Chahroudi, Ann ; Bosinger, Steven E ; Yoon, Jack ; Cox, Bryan ; Silvestri, Guido ; Kulpa, Deanna A
Publisher:United States: Public Library of Science
Journal title:PLoS pathogens, 2020-09, Vol.16 (9), p.e1008821-e1008821
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The role of CD101-expressing CD4 T cells in HIV/SIV pathogenesis and persistence
Author / Creator:Strongin, Zachary ; Hoang, Timothy N ; Tharp, Gregory K ; Rahmberg, Andrew R ; Harper, Justin L ; Nguyen, Kevin ; Franchitti, Lavinia ; Cervasi, Barbara ; Lee, Max ; Zhang, Zhan ; Boritz, Eli A ; Silvestri, Guido ; Marconi, Vincent C ; Bosinger, Steven E ; Brenchley, Jason M ; Kulpa, Deanna A ; Paiardini, Mirko
Publisher:United States: Public Library of Science
Journal title:PLoS pathogens, 2022-07, Vol.18 (7), p.e1010723-e1010723
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ArticlesPeer ReviewedFull Text
Damaged intestinal epithelial integrity linked to microbial translocation in pathogenic simian immunodeficiency virus infections
Author / Creator:Estes, Jacob D ; Harris, Levelle D ; Klatt, Nichole R ; Tabb, Brian ; Pittaluga, Stefania ; Paiardini, Mirko ; Barclay, G Robin ; Smedley, Jeremy ; Pung, Rhonda ; Oliveira, Kenneth M ; Hirsch, Vanessa M ; Silvestri, Guido ; Douek, Daniel C ; Miller, Christopher J ; Haase, Ashley T ; Lifson, Jeffrey ; Brenchley, Jason M
Publisher:United States: Public Library of Science
Journal title:PLoS pathogens, 2010-08, Vol.6 (8), p.e1001052-e1001052
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Interleukin-10 contributes to reservoir establishment and persistence in SIV-infected macaques treated with antiretroviral therapy
Author / Creator:Harper, Justin ; Ribeiro, Susan P ; Chan, Chi Ngai ; Aid, Malika ; Deleage, Claire ; Micci, Luca ; Pino, Maria ; Cervasi, Barbara ; Raghunathan, Gopalan ; Rimmer, Eric ; Ayanoglu, Gulesi ; Wu, Guoxin ; Shenvi, Neeta ; Barnard, Richard Jo ; Del Prete, Gregory Q ; Busman-Sahay, Kathleen ; Silvestri, Guido ; Kulpa, Deanna A ; Bosinger, Steven E ; Easley, Kirk A ; Howell, Bonnie J ; Gorman, Dan ; Hazuda, Daria J ; Estes, Jacob D ; Sekaly, Rafick-Pierre ; Paiardini, Mirko
Publisher:United States: American Society for Clinical Investigation
Journal title:The Journal of clinical investigation, 2022-04, Vol.132 (8), p.1-17
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Global genomic analysis reveals rapid control of a robust innate response in SIV-infected sooty mangabeys
Author / Creator:Bosinger, Steven E ; Li, Qingsheng ; Gordon, Shari N ; Klatt, Nichole R ; Duan, Lijie ; Xu, Luoling ; Francella, Nicholas ; Sidahmed, Abubaker ; Smith, Anthony J ; Cramer, Elizabeth M ; Zeng, Ming ; Masopust, David ; Carlis, John V ; Ran, Longsi ; Vanderford, Thomas H ; Paiardini, Mirko ; Isett, R Benjamin ; Baldwin, Don A ; Else, James G ; Staprans, Silvija I ; Silvestri, Guido ; Haase, Ashley T ; Kelvin, David J
Publisher:United States: American Society for Clinical Investigation
Journal title:The Journal of clinical investigation, 2009-12, Vol.119 (12), p.3556-3572
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Timing of initiation of anti-retroviral therapy predicts post-treatment control of SIV replication
Author / Creator:Pinkevych, Mykola ; Docken, Steffen S ; Okoye, Afam A ; Fennessey, Christine M ; Del Prete, Gregory Q ; Pino, Maria ; Harper, Justin L ; Betts, Michael R ; Paiardini, Mirko ; Keele, Brandon F ; Davenport, Miles P
Publisher:United States: Public Library of Science
Journal title:PLoS pathogens, 2023-10, Vol.19 (10), p.e1011660-e1011660
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Multiplatform analyses reveal distinct drivers of systemic pathogenesis in adult versus pediatric severe acute COVID-19
Author / Creator:Druzak, Samuel ; Iffrig, Elizabeth ; Roberts, Blaine R. ; Zhang, Tiantian ; Fibben, Kirby S. ; Sakurai, Yumiko ; Verkerke, Hans P. ; Rostad, Christina A. ; Chahroudi, Ann ; Schneider, Frank ; Wong, Andrew Kam Ho ; Roberts, Anne M. ; Chandler, Joshua D. ; Kim, Susan O. ; Mosunjac, Mario ; Mosunjac, Marina ; Geller, Rachel ; Albizua, Igor ; Stowell, Sean R. ; Arthur, Connie M. ; Anderson, Evan J. ; Ivanova, Anna A. ; Ahn, Jun ; Liu, Xueyun ; Maner-Smith, Kristal ; Bowen, Thomas ; Paiardini, Mirko ; Bosinger, Steve E. ; Roback, John D. ; Kulpa, Deanna A. ; Silvestri, Guido ; Lam, Wilbur A. ; Ortlund, Eric A. ; Maier, Cheryl L.
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2023-04, Vol.14 (1), p.1638-1638, Article 1638
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Loss of Function of Intestinal IL-17 and IL-22 Producing Cells Contributes to Inflammation and Viral Persistence in SIV-Infected Rhesus Macaques
Author / Creator:Ryan, Emily S ; Micci, Luca ; Fromentin, Rémi ; Paganini, Sara ; McGary, Colleen S ; Easley, Kirk ; Chomont, Nicolas ; Paiardini, Mirko
Publisher:United States: Public Library of Science
Journal title:PLoS pathogens, 2016-02, Vol.12 (2), p.e1005412-e1005412
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TREM2+ and interstitial-like macrophages orchestrate airway inflammation in SARS-CoV-2 infection in rhesus macaques
Author / Creator:Upadhyay, Amit A. ; Viox, Elise G. ; Hoang, Timothy N. ; Boddapati, Arun K. ; Pino, Maria ; Lee, Michelle Y.-H. ; Corry, Jacqueline ; Strongin, Zachary ; Cowan, David A. ; Beagle, Elizabeth N. ; Horton, Tristan R. ; Hamilton, Sydney ; Aoued, Hadj ; Harper, Justin L. ; Edwards, Christopher T. ; Nguyen, Kevin ; Pellegrini, Kathryn L. ; Tharp, Gregory K. ; Piantadosi, Anne ; Levit, Rebecca D. ; Amara, Rama R. ; Barratt-Boyes, Simon M. ; Ribeiro, Susan P. ; Sekaly, Rafick P. ; Vanderford, Thomas H. ; Schinazi, Raymond F. ; Paiardini, Mirko ; Bosinger, Steven E.
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2023-04, Vol.14 (1), p.1914-16, Article 1914
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Preferential selection of viral escape mutants by CD8+ T cell 'sieving' of SIV reactivation from latency
Author / Creator:Docken, Steffen S ; McCormick, Kevin ; Pampena, M Betina ; Samer, Sadia ; Lindemuth, Emily ; Pinkevych, Mykola ; Viox, Elise G ; Wu, Yuhuang ; Schlub, Timothy E ; Cromer, Deborah ; Keele, Brandon F ; Paiardini, Mirko ; Betts, Michael R ; Bar, Katharine J ; Davenport, Miles P
Publisher:United States: Public Library of Science
Journal title:PLoS pathogens, 2023-11, Vol.19 (11), p.e1011755-e1011755
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CD4 depletion in SIV-infected macaques results in macrophage and microglia infection with rapid turnover of infected cells
Author / Creator:Micci, Luca ; Alvarez, Xavier ; Iriele, Robin I ; Ortiz, Alexandra M ; Ryan, Emily S ; McGary, Colleen S ; Deleage, Claire ; McAtee, Brigitte B ; He, Tianyu ; Apetrei, Cristian ; Easley, Kirk ; Pahwa, Savita ; Collman, Ronald G ; Derdeyn, Cynthia A ; Davenport, Miles P ; Estes, Jacob D ; Silvestri, Guido ; Lackner, Andrew A ; Paiardini, Mirko
Publisher:United States: Public Library of Science
Journal title:PLoS pathogens, 2014-10, Vol.10 (10), p.e1004467
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Passive infusion of an S2-Stem broadly neutralizing antibody protects against SARS-CoV-2 infection and lower airway inflammation in rhesus macaques
Author / Creator:Edwards, Christopher T ; Karunakaran, Kirti A ; Garcia, Elijah ; Beutler, Nathan ; Gagne, Matthew ; Golden, Nadia ; Aoued, Hadj ; Pellegrini, Kathryn L ; Burnett, Matthew R ; Honeycutt, Christopher Cole ; Lapp, Stacey A ; Ton, Thang ; Lin, Mark C ; Metz, Amanda ; Bombin, Andrei ; Goff, Kelly ; Scheuermann, Sarah E ; Wilkes, Amelia ; Wood, Jennifer S ; Ehnert, Stephanie ; Weissman, Stacey ; Curran, Elizabeth H ; Roy, Melissa ; Dessasau, Evan ; Paiardini, Mirko ; Upadhyay, Amit A ; Moore, Ian N ; Maness, Nicholas J ; Douek, Daniel C ; Piantadosi, Anne ; Andrabi, Raiees ; Rogers, Thomas R ; Burton, Dennis R ; Bosinger, Steven E
Publisher:United States: Public Library of Science
Journal title:PLoS pathogens, 2025-01, Vol.21 (1), p.e1012456
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Paiardini, Mirko

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Paiardini, Mirko

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Robust and persistent reactivation of SIV and HIV by N-803 and depletion of CD8+ cells

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Natural SIV Hosts: Showing AIDS the Door

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IL-21 and IFNα therapy rescues terminally differentiated NK cells and limits SIV reservoir in ART-treated macaques

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Recommendations for measuring HIV reservoir size in cure-directed clinical trials

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SIV-induced terminally differentiated adaptive NK cells in lymph nodes associated with enhanced MHC-E restricted activity

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CTLA-4 and PD-1 dual blockade induces SIV reactivation without control of rebound after antiretroviral therapy interruption

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Innate, non-cytolytic CD8+ T cell-mediated suppression of HIV replication by MHC-independent inhibition of virus transcription

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The role of CD101-expressing CD4 T cells in HIV/SIV pathogenesis and persistence

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Damaged intestinal epithelial integrity linked to microbial translocation in pathogenic simian immunodeficiency virus infections

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Interleukin-10 contributes to reservoir establishment and persistence in SIV-infected macaques treated with antiretroviral therapy

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Global genomic analysis reveals rapid control of a robust innate response in SIV-infected sooty mangabeys

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Timing of initiation of anti-retroviral therapy predicts post-treatment control of SIV replication

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Multiplatform analyses reveal distinct drivers of systemic pathogenesis in adult versus pediatric severe acute COVID-19

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Loss of Function of Intestinal IL-17 and IL-22 Producing Cells Contributes to Inflammation and Viral Persistence in SIV-Infected Rhesus Macaques

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TREM2+ and interstitial-like macrophages orchestrate airway inflammation in SARS-CoV-2 infection in rhesus macaques

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Preferential selection of viral escape mutants by CD8+ T cell 'sieving' of SIV reactivation from latency

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CD4 depletion in SIV-infected macaques results in macrophage and microglia infection with rapid turnover of infected cells

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Passive infusion of an S2-Stem broadly neutralizing antibody protects against SARS-CoV-2 infection and lower airway inflammation in rhesus macaques

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