GABA uptake transporters support dopamine release in dorsal striatum with maladaptive downregulation...
GABA uptake transporters support dopamine release in dorsal striatum with maladaptive downregulation in a parkinsonism model
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London: Nature Publishing Group UK
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Language
English
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London: Nature Publishing Group UK
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Striatal dopamine (DA) is critical for action and learning. Recent data show that DA release is under tonic inhibition by striatal GABA. Ambient striatal GABA tone on striatal projection neurons can be determined by plasma membrane GABA uptake transporters (GATs) located on astrocytes and neurons. However, whether striatal GATs and astrocytes deter...
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Full title
GABA uptake transporters support dopamine release in dorsal striatum with maladaptive downregulation in a parkinsonism model
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TN_cdi_doaj_primary_oai_doaj_org_article_f4c24c167c97494e92ebdf24a5229496
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_f4c24c167c97494e92ebdf24a5229496
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ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-020-18247-5
