The nuclear import of the transcription factor MyoD is reduced in mesenchymal stem cells grown in a...
The nuclear import of the transcription factor MyoD is reduced in mesenchymal stem cells grown in a 3D micro-engineered niche
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Publisher
London: Nature Publishing Group UK
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Language
English
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London: Nature Publishing Group UK
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Smart biomaterials are increasingly being used to control stem cell fate in vitro by the recapitulation of the native niche microenvironment. By integrating experimental measurements with numerical models, we show that in mesenchymal stem cells grown inside a 3D synthetic niche both nuclear transport of a myogenic factor and the passive nuclear dif...
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Full title
The nuclear import of the transcription factor MyoD is reduced in mesenchymal stem cells grown in a 3D micro-engineered niche
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TN_cdi_doaj_primary_oai_doaj_org_article_f506a71168f74e929134b61056b23a77
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_f506a71168f74e929134b61056b23a77
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ISSN
2045-2322
E-ISSN
2045-2322
DOI
10.1038/s41598-021-81920-2
