The "One-Step" approach for QT analysis increases the sensitivity of nonclinical QTc analysis
The "One-Step" approach for QT analysis increases the sensitivity of nonclinical QTc analysis
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United States: John Wiley & Sons, Inc
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English
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United States: John Wiley & Sons, Inc
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Whether a compound prolongs cardiac repolarization independent of changes in beat rate is a critical question in drug research and development. Current practice is to resolve this in two steps. First, the QT interval is corrected for the influence of rate and then statistical significance is tested. There is renewed interest in improving the sensit...
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The "One-Step" approach for QT analysis increases the sensitivity of nonclinical QTc analysis
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TN_cdi_doaj_primary_oai_doaj_org_article_f535042826c449bc83fae85741c955af
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_f535042826c449bc83fae85741c955af
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ISSN
1752-8054
E-ISSN
1752-8062
DOI
10.1111/cts.13625
