scSNPdemux: a sensitive demultiplexing pipeline using single nucleotide polymorphisms for improved p...
scSNPdemux: a sensitive demultiplexing pipeline using single nucleotide polymorphisms for improved pooled single-cell RNA sequencing analysis
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Publisher
London: BioMed Central Ltd
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Language
English
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London: BioMed Central Ltd
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Here we present scSNPdemux, a sample demultiplexing pipeline for single-cell RNA sequencing data using natural genetic variations in humans. The pipeline requires alignment files from Cell Ranger (10x Genomics), a population SNP database and genotyped single nucleotide polymorphisms (SNPs) per sample. The tool works on sparse genotyping data in VCF...
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Full title
scSNPdemux: a sensitive demultiplexing pipeline using single nucleotide polymorphisms for improved pooled single-cell RNA sequencing analysis
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TN_cdi_doaj_primary_oai_doaj_org_article_f552b0897e864f92bec52c1fbb48ac58
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_f552b0897e864f92bec52c1fbb48ac58
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ISSN
1471-2105
E-ISSN
1471-2105
DOI
10.1186/s12859-023-05440-8
