SerpinA3N is a novel hypothalamic gene upregulated by a high-fat diet and leptin in mice
SerpinA3N is a novel hypothalamic gene upregulated by a high-fat diet and leptin in mice
About this item
Full title
Author / Creator
Sergi, Domenico , Campbell, Fiona M , Grant, Christine , Morris, Amanda C , Bachmair, Eva-Maria , Koch, Christiane , McLean, Fiona H , Muller, Aifric , Hoggard, Nigel , de Roos, Baukje , Porteiro, Begona , Boekschoten, Mark V , McGillicuddy, Fiona C , Kahn, Darcy , Nicol, Phyllis , Benzler, Jonas , Mayer, Claus-Dieter , Drew, Janice E , Roche, Helen M , Muller, Michael , Nogueiras, Ruben , Dieguez, Carlos , Tups, Alexander and Williams, Lynda M
Publisher
Germany: BioMed Central
Journal title
Language
English
Formats
Publication information
Publisher
Germany: BioMed Central
Subjects
More information
Scope and Contents
Contents
Energy homeostasis is regulated by the hypothalamus but fails when animals are fed a high-fat diet (HFD), and leptin insensitivity and obesity develops. To elucidate the possible mechanisms underlying these effects, a microarray-based transcriptomics approach was used to identify novel genes regulated by HFD and leptin in the mouse hypothalamus.
Alternative Titles
Full title
SerpinA3N is a novel hypothalamic gene upregulated by a high-fat diet and leptin in mice
Authors, Artists and Contributors
Author / Creator
Campbell, Fiona M
Grant, Christine
Morris, Amanda C
Bachmair, Eva-Maria
Koch, Christiane
McLean, Fiona H
Muller, Aifric
Hoggard, Nigel
de Roos, Baukje
Porteiro, Begona
Boekschoten, Mark V
McGillicuddy, Fiona C
Kahn, Darcy
Nicol, Phyllis
Benzler, Jonas
Mayer, Claus-Dieter
Drew, Janice E
Roche, Helen M
Muller, Michael
Nogueiras, Ruben
Dieguez, Carlos
Tups, Alexander
Williams, Lynda M
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_f5bb12ec5e87442284aa5620612107c2
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_f5bb12ec5e87442284aa5620612107c2
Other Identifiers
ISSN
1555-8932
E-ISSN
1865-3499
DOI
10.1186/s12263-018-0619-1
