Uncovering novel KCC2 regulatory motifs through a comprehensive transposon-based mutant library
Uncovering novel KCC2 regulatory motifs through a comprehensive transposon-based mutant library
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Switzerland: Frontiers Research Foundation
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Language
English
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Switzerland: Frontiers Research Foundation
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The neuron-specific K-Cl cotransporter KCC2 maintains low intracellular chloride levels, which are crucial for fast GABAergic and glycinergic neurotransmission. KCC2 also plays a pivotal role in the development of excitatory glutamatergic neurotransmission by promoting dendritic spine maturation. The cytoplasmic C-terminal domain (KCC2-CTD) plays a...
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Uncovering novel KCC2 regulatory motifs through a comprehensive transposon-based mutant library
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TN_cdi_doaj_primary_oai_doaj_org_article_f5d2c0a68cd04b12a1c0874653c42bfb
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_f5d2c0a68cd04b12a1c0874653c42bfb
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ISSN
1662-5099
E-ISSN
1662-5099
DOI
10.3389/fnmol.2024.1505722
