Astrocyte-derived exosomal nicotinamide phosphoribosyltransferase (Nampt) ameliorates ischemic strok...
Astrocyte-derived exosomal nicotinamide phosphoribosyltransferase (Nampt) ameliorates ischemic stroke injury by targeting AMPK/mTOR signaling to induce autophagy
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Author / Creator
Deng, Yang , Duan, Rui , Ding, Wangli , Gu, Qiuchen , Liu, Manman , Zhou, Junshan , Sun, Jianguo and Zhu, Junrong
Publisher
London: Nature Publishing Group UK
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Language
English
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Publisher
London: Nature Publishing Group UK
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Contents
Acute ischemic stroke (AIS) is a global cerebrovascular disease with high disability and mortality, which has no effective therapy. Studies have demonstrated that astrocyte-derived exosomes (ADEXs) provided neuroprotection in experimental stroke models. Nevertheless, the role of exosomes derived from oxygen-glucose-deprivation/reoxygenation-stimula...
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Full title
Astrocyte-derived exosomal nicotinamide phosphoribosyltransferase (Nampt) ameliorates ischemic stroke injury by targeting AMPK/mTOR signaling to induce autophagy
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TN_cdi_doaj_primary_oai_doaj_org_article_f6658f17109d43dabbb3bd536f1a978a
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_f6658f17109d43dabbb3bd536f1a978a
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ISSN
2041-4889
E-ISSN
2041-4889
DOI
10.1038/s41419-022-05454-9
