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The Epigenetic Dimension of Protein Structure Is an Intrinsic Weakness of the AlphaFold Program

The Epigenetic Dimension of Protein Structure Is an Intrinsic Weakness of the AlphaFold Program

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_f6667eb16ff74ee3a16272e119a9ec72

The Epigenetic Dimension of Protein Structure Is an Intrinsic Weakness of the AlphaFold Program

About this item

Full title

The Epigenetic Dimension of Protein Structure Is an Intrinsic Weakness of the AlphaFold Program

Publisher

Basel: MDPI AG

Journal title

Biomolecules (Basel, Switzerland), 2022-10, Vol.12 (10), p.1527

Language

English

Formats

Publication information

Publisher

Basel: MDPI AG

More information

Scope and Contents

Contents

One of the most important lessons we have learned from sequencing the human genome is that not all proteins have a 3D structure. In fact, a large part of the human proteome is made up of intrinsically disordered proteins (IDPs) which can adopt multiple structures, and therefore, multiple functions, depending on the ligands with which they interact....

Alternative Titles

Full title

The Epigenetic Dimension of Protein Structure Is an Intrinsic Weakness of the AlphaFold Program

Authors, Artists and Contributors

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_f6667eb16ff74ee3a16272e119a9ec72

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_f6667eb16ff74ee3a16272e119a9ec72

Other Identifiers

ISSN

2218-273X

E-ISSN

2218-273X

DOI

10.3390/biom12101527

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