The Epigenetic Dimension of Protein Structure Is an Intrinsic Weakness of the AlphaFold Program
The Epigenetic Dimension of Protein Structure Is an Intrinsic Weakness of the AlphaFold Program
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Basel: MDPI AG
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English
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Basel: MDPI AG
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One of the most important lessons we have learned from sequencing the human genome is that not all proteins have a 3D structure. In fact, a large part of the human proteome is made up of intrinsically disordered proteins (IDPs) which can adopt multiple structures, and therefore, multiple functions, depending on the ligands with which they interact....
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The Epigenetic Dimension of Protein Structure Is an Intrinsic Weakness of the AlphaFold Program
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TN_cdi_doaj_primary_oai_doaj_org_article_f6667eb16ff74ee3a16272e119a9ec72
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_f6667eb16ff74ee3a16272e119a9ec72
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ISSN
2218-273X
E-ISSN
2218-273X
DOI
10.3390/biom12101527