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Genes driving three-dimensional growth of immortalized cells and cancer

Genes driving three-dimensional growth of immortalized cells and cancer

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_f68784099dc5481498402c50c02c37f1

Genes driving three-dimensional growth of immortalized cells and cancer

About this item

Full title

Genes driving three-dimensional growth of immortalized cells and cancer

Publisher

London: Nature Publishing Group UK

Journal title

Cell death & disease, 2025-06, Vol.16 (1), p.442-11

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

Unchecked growth in three-dimensions (3D) in culture is a key feature of immortalized cells on the path to malignant transformation and hence a potential target phenotype for prevention. Also, expression of genes driving this process, but not that of 2D growth, would likely be more specific to cancer development and their inhibition would be less t...

Alternative Titles

Full title

Genes driving three-dimensional growth of immortalized cells and cancer

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_f68784099dc5481498402c50c02c37f1

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_f68784099dc5481498402c50c02c37f1

Other Identifiers

ISSN

2041-4889

E-ISSN

2041-4889

DOI

10.1038/s41419-025-07719-5

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