Vagus-macrophage-hepatocyte link promotes post-injury liver regeneration and whole-body survival thr...
Vagus-macrophage-hepatocyte link promotes post-injury liver regeneration and whole-body survival through hepatic FoxM1 activation
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Author / Creator
Izumi, Tomohito , Imai, Junta , Yamamoto, Junpei , Kawana, Yohei , Endo, Akira , Sugawara, Hiroto , Kohata, Masato , Asai, Yoichiro , Takahashi, Kei , Kodama, Shinjiro , Kaneko, Keizo , Gao, Junhong , Uno, Kenji , Sawada, Shojiro , Kalinichenko, Vladimir V. , Ishigaki, Yasushi , Yamada, Tetsuya and Katagiri, Hideki
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
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Publication information
Publisher
London: Nature Publishing Group UK
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Scope and Contents
Contents
The liver possesses a high regenerative capacity. Liver regeneration is a compensatory response overcoming disturbances of whole-body homeostasis provoked by organ defects. Here we show that a vagus-macrophage-hepatocyte link regulates acute liver regeneration after liver injury and that this system is critical for promoting survival. Hepatic
Fo...
Alternative Titles
Full title
Vagus-macrophage-hepatocyte link promotes post-injury liver regeneration and whole-body survival through hepatic FoxM1 activation
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Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_f719e1036e594ff69a5c540261de719c
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_f719e1036e594ff69a5c540261de719c
Other Identifiers
ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-018-07747-0
