Deciphering spatial genomic heterogeneity at a single cell resolution in multiple myeloma
Deciphering spatial genomic heterogeneity at a single cell resolution in multiple myeloma
About this item
Full title
Author / Creator
Merz, Maximilian , Merz, Almuth Maria Anni , Wang, Jie , Wei, Lei , Hu, Qiang , Hutson, Nicholas , Rondeau, Cherie , Celotto, Kimberly , Belal, Ahmed , Alberico, Ronald , Block, AnneMarie W. , Mohammadpour, Hemn , Wallace, Paul K. , Tario, Joseph , Luce, Jesse , Glenn, Sean T. , Singh, Prashant , Herr, Megan M. , Hahn, Theresa , Samur, Mehmet , Munshi, Nikhil , Liu, Song , McCarthy, Philip L. and Hillengass, Jens
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
Formats
Publication information
Publisher
London: Nature Publishing Group UK
Subjects
More information
Scope and Contents
Contents
Osteolytic lesions (OL) characterize symptomatic multiple myeloma. The mechanisms of how malignant plasma cells (PC) cause OL in one region while others show no signs of bone destruction despite subtotal infiltration remain unknown. We report on a single-cell RNA sequencing (scRNA-seq) study of PC obtained prospectively from random bone marrow aspi...
Alternative Titles
Full title
Deciphering spatial genomic heterogeneity at a single cell resolution in multiple myeloma
Authors, Artists and Contributors
Author / Creator
Merz, Almuth Maria Anni
Wang, Jie
Wei, Lei
Hu, Qiang
Hutson, Nicholas
Rondeau, Cherie
Celotto, Kimberly
Belal, Ahmed
Alberico, Ronald
Block, AnneMarie W.
Mohammadpour, Hemn
Wallace, Paul K.
Tario, Joseph
Luce, Jesse
Glenn, Sean T.
Singh, Prashant
Herr, Megan M.
Hahn, Theresa
Samur, Mehmet
Munshi, Nikhil
Liu, Song
McCarthy, Philip L.
Hillengass, Jens
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_f796828f91bf49deafc2d56948663af8
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_f796828f91bf49deafc2d56948663af8
Other Identifiers
ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-022-28266-z
