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A Myb enhancer-guided analysis of basophil and mast cell differentiation

A Myb enhancer-guided analysis of basophil and mast cell differentiation

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_f7b34ab06eff47b1947cf8949cde1d29

A Myb enhancer-guided analysis of basophil and mast cell differentiation

About this item

Full title

A Myb enhancer-guided analysis of basophil and mast cell differentiation

Publisher

London: Nature Publishing Group UK

Journal title

Nature communications, 2022-11, Vol.13 (1), p.7064-7064, Article 7064

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

The transcription factor MYB is a crucial regulator of hematopoietic stem and progenitor cells. However, the nature of lineage-specific enhancer usage of the
Myb
gene is largely unknown. We identify the
Myb
−68 enhancer, a regulatory element which marks basophils and mast cells. Using the
Myb
−68 enhancer activity, we show a popul...

Alternative Titles

Full title

A Myb enhancer-guided analysis of basophil and mast cell differentiation

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_f7b34ab06eff47b1947cf8949cde1d29

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_f7b34ab06eff47b1947cf8949cde1d29

Other Identifiers

ISSN

2041-1723

E-ISSN

2041-1723

DOI

10.1038/s41467-022-34906-1

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