Co-activation of super-enhancer-driven CCAT1 by TP63 and SOX2 promotes squamous cancer progression
Co-activation of super-enhancer-driven CCAT1 by TP63 and SOX2 promotes squamous cancer progression
About this item
Full title
Author / Creator
Jiang, Yuan , Jiang, Yan-Yi , Xie, Jian-Jun , Mayakonda, Anand , Hazawa, Masaharu , Chen, Li , Xiao, Jin-Fen , Li, Chun-Quan , Huang, Mo-Li , Ding, Ling-Wen , Sun, Qiao-Yang , Xu, Liang , Kanojia, Deepika , Jeitany, Maya , Deng, Jian-Wen , Liao, Lian-Di , Soukiasian, Harmik J. , Berman, Benjamin P. , Hao, Jia-Jie , Xu, Li-Yan , Li, En-Min , Wang, Ming-Rong , Bi, Xin-Gang , Lin, De-Chen and Koeffler, H. Phillip
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
Formats
Publication information
Publisher
London: Nature Publishing Group UK
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More information
Scope and Contents
Contents
Squamous cell carcinomas (SCCs) are aggressive malignancies. Previous report demonstrated that master transcription factors (TFs) TP63 and SOX2 exhibited overlapping genomic occupancy in SCCs. However, functional consequence of their frequent co-localization at super-enhancers remains incompletely understood. Here, epigenomic profilings of differen...
Alternative Titles
Full title
Co-activation of super-enhancer-driven CCAT1 by TP63 and SOX2 promotes squamous cancer progression
Authors, Artists and Contributors
Author / Creator
Jiang, Yan-Yi
Xie, Jian-Jun
Mayakonda, Anand
Hazawa, Masaharu
Chen, Li
Xiao, Jin-Fen
Li, Chun-Quan
Huang, Mo-Li
Ding, Ling-Wen
Sun, Qiao-Yang
Xu, Liang
Kanojia, Deepika
Jeitany, Maya
Deng, Jian-Wen
Liao, Lian-Di
Soukiasian, Harmik J.
Berman, Benjamin P.
Hao, Jia-Jie
Xu, Li-Yan
Li, En-Min
Wang, Ming-Rong
Bi, Xin-Gang
Lin, De-Chen
Koeffler, H. Phillip
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_f927ec3e43a241b38907cdd1a8dba8c5
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_f927ec3e43a241b38907cdd1a8dba8c5
Other Identifiers
ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-018-06081-9
