Inactivation of Sirt6 ameliorates muscular dystrophy in mdx mice by releasing suppression of utrophi...
Inactivation of Sirt6 ameliorates muscular dystrophy in mdx mice by releasing suppression of utrophin expression
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London: Nature Publishing Group UK
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Language
English
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London: Nature Publishing Group UK
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The NAD
+
-dependent SIRT1-7 family of protein deacetylases plays a vital role in various molecular pathways related to stress response, DNA repair, aging and metabolism. Increased activity of individual sirtuins often exerts beneficial effects in pathophysiological conditions whereas reduced activity is usually associated with disease condit...
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Inactivation of Sirt6 ameliorates muscular dystrophy in mdx mice by releasing suppression of utrophin expression
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TN_cdi_doaj_primary_oai_doaj_org_article_f98f5858e11c424f9ecb03f39cf07309
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_f98f5858e11c424f9ecb03f39cf07309
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ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-022-31798-z
