An Isolated Limb Infusion Method Allows for Broad Distribution of rAAVrh74.MCK.GALGT2 to Leg Skeleta...
An Isolated Limb Infusion Method Allows for Broad Distribution of rAAVrh74.MCK.GALGT2 to Leg Skeletal Muscles in the Rhesus Macaque
About this item
Full title
Author / Creator
Xu, Rui , Jia, Ying , Zygmunt, Deborah A. , Cramer, Megan L. , Crowe, Kelly E. , Shao, Guohong , Maki, Agatha E. , Guggenheim, Haley N. , Hood, Benjamin C. , Griffin, Danielle A. , Peterson, Ellyn , Bolon, Brad , Cheatham, John P. , Cheatham, Sharon L. , Flanigan, Kevin M. , Rodino-Klapac, Louise R. , Chicoine, Louis G. and Martin, Paul T.
Publisher
Elsevier Inc
Journal title
Language
English
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Publication information
Publisher
Elsevier Inc
Subjects
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Scope and Contents
Contents
Recombinant adeno-associated virus (rAAV)rh74.MCK.GALGT2 is a muscle-specific gene therapy that is being developed to treat forms of muscular dystrophy. Here we report on an isolated limb infusion technique in a non-human primate model, where hindlimb blood flow is transiently isolated using balloon catheters to concentrate vector in targeted leg m...
Alternative Titles
Full title
An Isolated Limb Infusion Method Allows for Broad Distribution of rAAVrh74.MCK.GALGT2 to Leg Skeletal Muscles in the Rhesus Macaque
Authors, Artists and Contributors
Author / Creator
Jia, Ying
Zygmunt, Deborah A.
Cramer, Megan L.
Crowe, Kelly E.
Shao, Guohong
Maki, Agatha E.
Guggenheim, Haley N.
Hood, Benjamin C.
Griffin, Danielle A.
Peterson, Ellyn
Bolon, Brad
Cheatham, John P.
Cheatham, Sharon L.
Flanigan, Kevin M.
Rodino-Klapac, Louise R.
Chicoine, Louis G.
Martin, Paul T.
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Primary Identifiers
Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_f9bc6cfb8158407cb2dff2b604340149
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_f9bc6cfb8158407cb2dff2b604340149
Other Identifiers
ISSN
2329-0501
E-ISSN
2329-0501
DOI
10.1016/j.omtm.2018.06.002
