Pre-symptomatic Caspase-1 inhibitor delays cognitive decline in a mouse model of Alzheimer disease a...
Pre-symptomatic Caspase-1 inhibitor delays cognitive decline in a mouse model of Alzheimer disease and aging
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Publisher
London: Nature Publishing Group UK
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Language
English
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London: Nature Publishing Group UK
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Early therapeutic interventions are essential to prevent Alzheimer Disease (AD). The association of several inflammation-related genetic markers with AD and the early activation of pro-inflammatory pathways in AD suggest inflammation as a plausible therapeutic target. Inflammatory Caspase-1 has a significant impact on AD-like pathophysiology and Ca...
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Pre-symptomatic Caspase-1 inhibitor delays cognitive decline in a mouse model of Alzheimer disease and aging
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TN_cdi_doaj_primary_oai_doaj_org_article_f9e708e8e4a94657bdc8e388bc81fd42
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_f9e708e8e4a94657bdc8e388bc81fd42
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ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-020-18405-9
