Distant relatives of a eukaryotic cell-specific toxin family evolved a complement-like mechanism to...
Distant relatives of a eukaryotic cell-specific toxin family evolved a complement-like mechanism to kill bacteria
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Publisher
London: Nature Publishing Group UK
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Language
English
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London: Nature Publishing Group UK
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Cholesterol-dependent cytolysins (CDCs) comprise a large family of pore-forming toxins produced by Gram-positive bacteria, which are used to attack eukaryotic cells. Here, we functionally characterize a family of 2-component CDC-like (CDCL) toxins produced by the Gram-negative Bacteroidota that form pores by a mechanism only described for the mamma...
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Distant relatives of a eukaryotic cell-specific toxin family evolved a complement-like mechanism to kill bacteria
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TN_cdi_doaj_primary_oai_doaj_org_article_fa81631103bf486aa966a456bbef1768
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_fa81631103bf486aa966a456bbef1768
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ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-024-49103-5
