ABCA1 is an extracellular phospholipid translocase
ABCA1 is an extracellular phospholipid translocase
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Publisher
London: Nature Publishing Group UK
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Language
English
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Publisher
London: Nature Publishing Group UK
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Contents
Production of high density lipoprotein (HDL) requires ATP-binding cassette transporter A1 (ABCA1) to drive phospholipid (PL) from the plasma membrane into extracellular apolipoprotein A-I. Here, we use simulations to show that domains of ABCA1 within the plasma membrane remove PL from the membrane’s outer leaflet. In our simulations, after the lipi...
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Full title
ABCA1 is an extracellular phospholipid translocase
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TN_cdi_doaj_primary_oai_doaj_org_article_fabaa2042cb346d69e7b13267b43befc
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_fabaa2042cb346d69e7b13267b43befc
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ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-022-32437-3
