Genome-wide tracking of dCas9-methyltransferase footprints
Genome-wide tracking of dCas9-methyltransferase footprints
About this item
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Author / Creator
Galonska, Christina , Charlton, Jocelyn , Mattei, Alexandra L. , Donaghey, Julie , Clement, Kendell , Gu, Hongcang , Mohammad, Arman W. , Stamenova, Elena K. , Cacchiarelli, Davide , Klages, Sven , Timmermann, Bernd , Cantz, Tobias , Schöler, Hans R. , Gnirke, Andreas , Ziller, Michael J. and Meissner, Alexander
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
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Publication information
Publisher
London: Nature Publishing Group UK
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More information
Scope and Contents
Contents
In normal mammalian development cytosine methylation is essential and is directed to specific regions of the genome. Despite notable advances through mapping its genome-wide distribution, studying the direct contribution of DNA methylation to gene and genome regulation has been limited by the lack of tools for its precise manipulation. Thus, combin...
Alternative Titles
Full title
Genome-wide tracking of dCas9-methyltransferase footprints
Authors, Artists and Contributors
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Primary Identifiers
Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_facfcb998fb94a91ab5dd5199cd3a1b4
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_facfcb998fb94a91ab5dd5199cd3a1b4
Other Identifiers
ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-017-02708-5
