Mechanisms of Pathogenic Tau and Aβ Protein Spreading in Alzheimer’s Disease
Mechanisms of Pathogenic Tau and Aβ Protein Spreading in Alzheimer’s Disease
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Lausanne: Frontiers Research Foundation
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Language
English
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Lausanne: Frontiers Research Foundation
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Contents
Alzheimer´s disease (AD) is pathologically defined by the presence of amyloid-β (Aβ) plaques, neurofibrillary tangles and neuronal loss. In general, the aggregation of Aβ is considered an essential trigger in AD pathogenesis that gives rise to neurofibrillary tangles, neuronal dysfunction and dementia. During the process leading to AD, tau and Aβ f...
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Full title
Mechanisms of Pathogenic Tau and Aβ Protein Spreading in Alzheimer’s Disease
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TN_cdi_doaj_primary_oai_doaj_org_article_fb33134c5cbe41f59b0ace44bca4a180
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_fb33134c5cbe41f59b0ace44bca4a180
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ISSN
1663-4365
E-ISSN
1663-4365
DOI
10.3389/fnagi.2020.00265
