Microglial Hyperreactivity Evolved to Immunosuppression in the Hippocampus of a Mouse Model of Accel...
Microglial Hyperreactivity Evolved to Immunosuppression in the Hippocampus of a Mouse Model of Accelerated Aging and Alzheimer's Disease Traits
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Switzerland: Frontiers Research Foundation
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English
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Switzerland: Frontiers Research Foundation
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Neuroinflammation is a risk factor for Alzheimer's disease (AD). We sought to study the glial derangement in AD using diverse experimental models and human brain tissue. Besides classical pro-inflammatory cytokines, we analyzed chitinase 3 like 1 (CHI3L1 or YKL40) and triggering receptor expressed on myeloid cells 2 (TREM2) that are increasingly be...
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Microglial Hyperreactivity Evolved to Immunosuppression in the Hippocampus of a Mouse Model of Accelerated Aging and Alzheimer's Disease Traits
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TN_cdi_doaj_primary_oai_doaj_org_article_fc07babb35f34ad6a9ddf288cd66838e
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_fc07babb35f34ad6a9ddf288cd66838e
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ISSN
1663-4365
E-ISSN
1663-4365
DOI
10.3389/fnagi.2020.622360
