The glycosyltransferase EXTL2 promotes proteoglycan deposition and injurious neuroinflammation follo...
The glycosyltransferase EXTL2 promotes proteoglycan deposition and injurious neuroinflammation following demyelination
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London: BioMed Central Ltd
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English
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London: BioMed Central Ltd
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Background Chondroitin sulfate proteoglycans (CSPGs) are potent inhibitors of axonal regrowth and remyelination. More recently, they have also been highlighted as a modulator of macrophage infiltration into the central nervous system in experimental autoimmune encephalomyelitis, an inflammatory model of multiple sclerosis. Methods We interrogated r...
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The glycosyltransferase EXTL2 promotes proteoglycan deposition and injurious neuroinflammation following demyelination
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TN_cdi_doaj_primary_oai_doaj_org_article_fcb02f3f24a64af28725f25f03251333
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_fcb02f3f24a64af28725f25f03251333
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ISSN
1742-2094
E-ISSN
1742-2094
DOI
10.1186/s12974-020-01895-1
