Embelin as Lead Compound for New Neuroserpin Polymerization Inhibitors
Embelin as Lead Compound for New Neuroserpin Polymerization Inhibitors
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Publisher
Basel: MDPI AG
Journal title
Language
English
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Publisher
Basel: MDPI AG
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Scope and Contents
Contents
Familial encephalopathy with neuroserpin inclusion bodies (FENIB) is a severe and lethal neurodegenerative disease. Upon specific point mutations in the SERPINI1gene-coding for the human protein neuroserpin (NS) the resulting pathologic NS variants polymerize and accumulate within the endoplasmic reticulum of neurons in the central nervous system....
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Full title
Embelin as Lead Compound for New Neuroserpin Polymerization Inhibitors
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Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_fdb1d61078384b278802ad76ea67ae50
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_fdb1d61078384b278802ad76ea67ae50
Other Identifiers
ISSN
2075-1729
E-ISSN
2075-1729
DOI
10.3390/life10070111
