Leukocyte integrin Mac-1 regulates thrombosis via interaction with platelet GPIbα
Leukocyte integrin Mac-1 regulates thrombosis via interaction with platelet GPIbα
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Publisher
London: Nature Publishing Group UK
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Language
English
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Publisher
London: Nature Publishing Group UK
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Contents
Inflammation and thrombosis occur together in many diseases. The leukocyte integrin Mac-1 (also known as integrin α
M
β
2
, or CD11b/CD18) is crucial for leukocyte recruitment to the endothelium, and Mac-1 engagement of platelet GPIbα is required for injury responses in diverse disease models. However, the role of Mac-1 in thrombosis is...
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Full title
Leukocyte integrin Mac-1 regulates thrombosis via interaction with platelet GPIbα
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TN_cdi_doaj_primary_oai_doaj_org_article_fde7eceb216348f28d8514ea1e616f3d
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_fde7eceb216348f28d8514ea1e616f3d
Other Identifiers
ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/ncomms15559
