Chromatin accessibility landscape of relapsed pediatric B-lineage acute lymphoblastic leukemia
Chromatin accessibility landscape of relapsed pediatric B-lineage acute lymphoblastic leukemia
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Author / Creator
Wang, Han , Sun, Huiying , Liang, Bilin , Zhang, Fang , Yang, Fan , Cui, Bowen , Ding, Lixia , Wang, Xiang , Wang, Ronghua , Cai, Jiaoyang , Tang, Yanjing , Rao, Jianan , Hu, Wenting , Zhao, Shuang , Wu, Wenyan , Chen, Xiaoxiao , Wu, Kefei , Lai, Junchen , Xie, Yangyang , Li, Benshang , Tang, Jingyan , Shen, Shuhong and Liu, Yu
Publisher
London: Nature Publishing Group UK
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Language
English
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Publisher
London: Nature Publishing Group UK
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Scope and Contents
Contents
For around half of the pediatric B-lineage acute lymphoblastic leukemia (B-ALL) patients, the molecular mechanism of relapse remains unclear. To fill this gap in knowledge, here we characterize the chromatin accessibility landscape in pediatric relapsed B-ALL. We observe rewired accessible chromatin regions (ACRs) associated with transcription dysr...
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Full title
Chromatin accessibility landscape of relapsed pediatric B-lineage acute lymphoblastic leukemia
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TN_cdi_doaj_primary_oai_doaj_org_article_fe96c0b766af471fa983e4b57c10585c
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_fe96c0b766af471fa983e4b57c10585c
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ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-023-42565-z
