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Glucocorticoid-dependent REDD1 expression reduces muscle metabolism to enable adaptation under energ...

Glucocorticoid-dependent REDD1 expression reduces muscle metabolism to enable adaptation under energ...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_fec9c00871564efe8cdbac8f34f294b2

Glucocorticoid-dependent REDD1 expression reduces muscle metabolism to enable adaptation under energetic stress

About this item

Full title

Glucocorticoid-dependent REDD1 expression reduces muscle metabolism to enable adaptation under energetic stress

Publisher

England: BioMed Central Ltd

Journal title

BMC biology, 2018-06, Vol.16 (1), p.65-65, Article 65

Language

English

Formats

Publication information

Publisher

England: BioMed Central Ltd

More information

Scope and Contents

Contents

Skeletal muscle atrophy is a common feature of numerous chronic pathologies and is correlated with patient mortality. The REDD1 protein is currently recognized as a negative regulator of muscle mass through inhibition of the Akt/mTORC1 signaling pathway. REDD1 expression is notably induced following glucocorticoid secretion, which is a component of...

Alternative Titles

Full title

Glucocorticoid-dependent REDD1 expression reduces muscle metabolism to enable adaptation under energetic stress

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_fec9c00871564efe8cdbac8f34f294b2

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_fec9c00871564efe8cdbac8f34f294b2

Other Identifiers

ISSN

1741-7007

E-ISSN

1741-7007

DOI

10.1186/s12915-018-0525-4

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