α‐Synuclein Pathology Spreads in a Midbrain–Hindbrain Assembloid Model
α‐Synuclein Pathology Spreads in a Midbrain–Hindbrain Assembloid Model
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Author / Creator
Gomez‐Giro, Gemma , Frangenberg, Daniela , Vega, Daniela , Zagare, Alise , Barmpa, Kyriaki , Antony, Paul M. A. , Robertson, Graham , Sabahi‐Kaviani, Rahman , Haendler, Kristian , Kruse, Nathalie , Papastefanaki, Florentia , Matsas, Rebecca , Spielmann, Malte , Luttge, Regina and Schwamborn, Jens C.
Publisher
Germany: John Wiley & Sons, Inc
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Language
English
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Publisher
Germany: John Wiley & Sons, Inc
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Contents
Understanding the progression of α‐synuclein pathology in neurodegenerative diseases such as Parkinson's disease (PD) is a longstanding challenge. Here, a novel midbrain–hindbrain‐assembloid model that recapitulates the spread of α‐synuclein pathology observed in PD patients, akin to Braak's hypothesis, is presented. Initially, the presence α‐synuc...
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Full title
α‐Synuclein Pathology Spreads in a Midbrain–Hindbrain Assembloid Model
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TN_cdi_doaj_primary_oai_doaj_org_article_ff038201aa6d49a2a01f2cf86e2b3f43
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_ff038201aa6d49a2a01f2cf86e2b3f43
Other Identifiers
ISSN
2198-3844
E-ISSN
2198-3844
DOI
10.1002/advs.202409040
