Molecular dioxygen enters the active site of 12/15-lipoxygenase via dynamic oxygen access channels
Molecular dioxygen enters the active site of 12/15-lipoxygenase via dynamic oxygen access channels
About this item
Full title
Author / Creator
Publisher
United States: National Academy of Sciences
Journal title
Language
English
Formats
Publication information
Publisher
United States: National Academy of Sciences
Subjects
More information
Scope and Contents
Contents
Cells contain numerous enzymes that use molecular oxygen for their reactions. Often, their active sites are buried deeply inside the protein, which raises the question whether there are specific access channels guiding oxygen to the site of catalysis. Choosing 12/15-lipoxygenase as a typical example for such oxygen-dependent enzymes, we determined...
Alternative Titles
Full title
Molecular dioxygen enters the active site of 12/15-lipoxygenase via dynamic oxygen access channels
Authors, Artists and Contributors
Author / Creator
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_fao_agris_US201300798980
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_fao_agris_US201300798980
Other Identifiers
ISSN
0027-8424
E-ISSN
1091-6490
DOI
10.1073/pnas.0702401104
